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Arthroplasty Complications clinical trials

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NCT ID: NCT06023238 Recruiting - Clinical trials for Arthroplasty Complications

Knee Prosthetic Joint Infection Antibiotic Elution

Start date: June 5, 2023
Phase:
Study type: Observational

Patients presenting with prosthetic joint infections of a total knee replacement who are treated with an antibiotic spacer will be observed prospectively for their response to treatment and antibiotic elution profiles will be measured post-operatively utilizing mass spectrometry from synovial fluid acquired as part of standard of care in the management of prosthetic joint infection. Secondary outcomes including post-operative complications, re-operation rates, and re-admission rates will also be compared.

NCT ID: NCT05974501 Completed - Postoperative Pain Clinical Trials

Pre vs Post Block in Total Knee Arthroplasty (TKA)

Start date: September 29, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee arthroplasty can be observed with the substitution of a post operative adductor canal block for a preoperative adductor canal block in the current established peri-operative pain protocol and if these changes lead to a decrease in opioid consumption (in morphine equivalents).

NCT ID: NCT05969366 Completed - Clinical trials for Arthroplasty Complications

Early Clinical and Radiological Outcomes of Uncemented Fully Coated Stem With Patients of 85 Years and More, Complications and Risks Factor

Start date: June 2015
Phase:
Study type: Observational

Retrospective, single-centre study. Review of patients aged 85 and over who underwent total hip replacement between June 2015 and February 2022. This is a femoral stem survival study with calculation of the complication rate in this population. The study does not focus on total hip replacements in the context of trauma. The secondary endpoint was the search for complication risk factors.

NCT ID: NCT05845021 Recruiting - Osteoporosis Clinical Trials

Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

Start date: September 27, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is: 1) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and fragility fractures when compared to standard of care primary care provider referral. Researchers will compare the endocrinology referral pathway and standard of care to see if there is a difference in treatment rates, fragility fractures, and implant-related complications following lower extremity arthroplasty.

NCT ID: NCT05736666 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement

Start date: October 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training. Perturbation training involves adjusting to rapid speed changes on a treadmill. The main questions it aims to answer are: - Does perturbation training improve the way that people who are planning to have total knee replacement surgery recover after treadmill test that reproduces a trip to the front or side? - Does perturbation training reduce the incidence of preventable gait-related falls during the first year after total knee replacement? Participants will: - complete surveys about their condition and fall history and take part in testing of walking ability and balance. - have a baseline gait analysis test to measure the motion of their body during normal walking. - Be randomized into two groups. One will receive fall-prevention literature. The other will receive the same literature and then take part in a two-week treadmill perturbation training program. - be contacted every two weeks for one year, and asked questions about whether they have fallen during that time. - wear an activity monitor on their wrist for one week periods, every three months. Researchers will compare the number of falls from the group that received literature to the treatment group to see if the training group has fewer falls during the year after surgery.

NCT ID: NCT05707234 Completed - Knee Osteoarthritis Clinical Trials

Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia

Start date: February 15, 2023
Phase: Phase 4
Study type: Interventional

For many years, total knee arthroplasty (TKA) has been a common and effective procedure to treat chronic refractory joint pain. Although efforts must be pursued, as general anesthesia remains the main tendency for TKA. Currently, the standard of care to manage procedural anxiety is pharmacological sedation; i.e. the intravenous administration of additional anesthetic agents such as propofol or midazolam. However, pharmacological sedation has considerable undesirable side effects. Hence, risks of intraprocedural adverse events including respiratory depression, hemodynamic perturbations, or paradoxical effects such as hostility, aggression, and psychomotor agitation, are increased. The goal of this prospective, single-center, randomized controlled clinical trial is to systematically evaluate the impact of implementing a protocol of virtual reality hypnosis in patients undergoing total knee arthroplasty under spinal anesthesia.

NCT ID: NCT05697965 Not yet recruiting - Clinical trials for Arthroplasty Complications

LocalVancomycinPowderToPreventPeriprostheticJointInfection.

Start date: March 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and complication profile of local vancomycin application in primary arthroplasty. The investigators hypothesized that the use of local antibiotics would decrease the rate of infection compared to controls and this will be achieved by applying 1 gm of vancomycin powder intracapsularly.

NCT ID: NCT05696418 Completed - Clinical trials for Arthroplasty Complications

Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Osteoarthritis is the most common cause of chronic joint disease, and its incidence has increased due to the high average life expectancy, in addition to the high incidence of obesity. Total knee arthroplasty is currently an accepted treatment for severe degenerative conditions and there are various implant systems with special features depending on component geometry, degree of fit of the articular surfaces, and fixation techniques. A tibial component with mobile polyethylene has been developed as an alternative to fixed polyethylene because it has theoretical advantages in terms of increasing the range of motion, reducing wear conditions, and reducing the incidence of anterior knee pain when the articular surface of the patella is not resurfaced.

NCT ID: NCT05691751 Completed - Blood Loss Clinical Trials

Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Tourniquet application in total knee arthroplasty has many benefits and might have a role in the incidence of peri-operative complications the aim of this research: is to look into the effectiveness of the limited application of tourniquet during primary unilateral total knee arthroplasty and compare the perioperative complications with the standard full-time application.

NCT ID: NCT05509946 Not yet recruiting - Clinical trials for Arthroplasty Complications

Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

Start date: October 1, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

This is a double-blinded randomized controlled trial aims to evaluate the effect of preemptive analgetic combination of celecoxib and pregabalin to acute pain after total hip arthroplasty. This study will be conducted in Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from October 2022 to April 2023. The subject of this study is adult patient who will be performed total hip arthroplasty.