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Arthropathy of Knee Joint clinical trials

View clinical trials related to Arthropathy of Knee Joint.

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NCT ID: NCT06124651 Completed - Clinical trials for Osteoarthritis, Knee

Comparison of Cruciate Retaining and Posterior Stabilized Total Knee Arthroplasty

Start date: January 1, 2004
Phase: N/A
Study type: Interventional

Several authors and large registries have suggested the potential for an increased risk of all-cause revision with the use of posterior cruciate-substitution (PS) total knee arthroplasty (TKA). The purpose of the current study was to compare posterior cruciate retaining (CR) and PS implants with respect to the functional and radiographic results, prevalence of osteolysis, revision rates and survivorship.

NCT ID: NCT05504577 Recruiting - Clinical trials for Arthropathy of Knee Joint

Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty

Start date: March 16, 2022
Phase: Phase 4
Study type: Interventional

This study is to conduct a prospective randomized controlled trial to investigate the blood-conservation effect of combination of intravenous TXA and QCG in a primary TKA procedure.

NCT ID: NCT05266027 Completed - Clinical trials for Arthropathy of Knee Joint

Naldebain for Pain Management After Knee Arthroplasty

Start date: April 6, 2022
Phase: Phase 4
Study type: Interventional

Naldebain, a long-acting analgesic injection, obtained a license from the Taiwan Food and Drug Administration (TFDA) of the Ministry of Health and Welfare on March 6, 2017 to approve a sustained-release long-acting analgesic on the market in Taiwan. This study hopes to use a rigorous double-blind randomized controlled experiment to understand whether the new sustained-release analgesic Naldebain can achieve effective pain relief for patients undergoing knee replacement surgery, and to evaluate the patient's functional recovery status .

NCT ID: NCT04814082 Recruiting - Knee Osteoarthritis Clinical Trials

Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives. Theoretically, achievement of normal knee motion using a medial pivot design in total knee replacements can be recreated in comparison to single radius designs, which could lead to an improvement in post-surgical outcomes and satisfaction with the procedure. The aim of this study is to compare two types of implant designs (medial pivot and single radius) in a total knee replacement using clinical outcomes, patient reported outcomes, and overall function assessed by a specialized gait laboratory.

NCT ID: NCT03668756 Completed - Clinical trials for Arthropathy of Knee Joint

Comparison of Computer-Assisted Navigation and Conventional Instrumentation for Bilateral Total Knee Arthroplasty

Start date: November 1, 2017
Phase:
Study type: Observational

To compare the functional outcomes of Computer-Assisted Navigation (CAS) and Conventional Instrumentation TKA at the 8-year follow-up.

NCT ID: NCT03647709 Completed - Clinical trials for Arthropathy of Knee Joint

Opioid-free Accelerated Recovery Total Knee Arthroplasty

Start date: October 1, 2018
Phase:
Study type: Observational

To prove that total knee arthroplasty can be performed with little, if any need for opioids by using a combination of patient education, optimized pre-op and post-op pain and recovery protocols. The goal being opioid-free total knee arthroplasty.

NCT ID: NCT03601728 Suspended - Clinical trials for Arthropathy of Knee Joint

A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The mission is to develop novel interventions to improve cognitive function, and thereby reducing delirium in hospitalized patients to improve perioperative outcomes. Delirium affects up to 42% of hospitalized patients and disproportionately increases morbidity and mortality in older adults, especially after surgical procedures. Current approaches prevent only 30-40% of delirium cases. The goal is to use prehabilitation (an individualized exercise regimen performed in the 2-4 weeks prior to admission) to improve peri-operative cognitive status, mobility and recovery. Based on preliminary data, the investigators propose to deeply phenotype patients, meaning to study the patient, the disease and surgery in a very detailed fashion, with elective knee or hip replacement surgery and use a personalized prehabilitation intervention compared to standard pre-operative care. To facilitate data collection over the course of the study, the investigators use wearable devices and mobile phone applications.

NCT ID: NCT03506347 Completed - Clinical trials for Arthropathy of Knee Joint

Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement

Start date: September 24, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more effective at obtaining adequate tissue levels of the antibiotic than the current standard dose which is given intravenously (IV) through a wrist vein. The use of intraosseous regional administration (IORA) of vancomycin requires the use of a tourniquet for the duration of the procedure. Many surgeons prefer to perform the surgery with tourniquet use minimised or without a tourniquet at all. The aim of this study is to evaluate whether IORA vancomycin can achieve effective tissue concentrations with tourniquet use minimised.

NCT ID: NCT03364088 Completed - Clinical trials for Rheumatoid Arthritis

Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia

Start date: October 3, 2016
Phase: N/A
Study type: Interventional
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NCT ID: NCT03339323 Recruiting - Knee Osteoarthritis Clinical Trials

The Effect of Exercise Training on Muscle Mass in Patients With Total Knee Arthroplasty

Start date: November 1, 2017
Phase: N/A
Study type: Interventional
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