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Arthritis clinical trials

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NCT ID: NCT03881059 Completed - Clinical trials for Active Psoriatic Arthritis

Efficacy and Safety of BMS-986165 Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA)

Start date: April 1, 2019
Phase: Phase 2
Study type: Interventional

The main purpose of study is to assess the dose-response relationship of BMS-986165 (Dose A or Dose B once daily [QD]) at Week 16 in the treatment of participants with active PsA.

NCT ID: NCT03876210 Completed - Arthritis Clinical Trials

Study to Compare the Safety and Pharmacokinetics of PK101 With Coadministration of the Two Separate Drugs

Start date: July 12, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the safety and pharmacokinetics of PK101(fixed-dose combination of PK101-001 and PK101-002) with coadministration of the two separate drugs in healthy volunteers.

NCT ID: NCT03868072 Completed - Clinical trials for Rheumatoid Arthritis

Study to Evaluate the Bioequivalence of Pfizer Korea Inc. "XELJANZ 5Mg Tablet" in Healthy Volunteers

Start date: February 22, 2019
Phase: Phase 1
Study type: Interventional

This study is an open-label, randomized, fasted, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tofacitinib Tablet" and Pfizer Korea Inc. "XELJANZ 5Mg Tablet" in healthy volunteers

NCT ID: NCT03858725 Completed - Clinical trials for Rheumatoid Arthritis

Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-374 5 mg in Healthy Volunteers

Start date: February 26, 2019
Phase: Phase 1
Study type: Interventional

This study is a randomized, open-label, fasted, single dose, crossover study to evaluate the pharmacokinetic profiles and safety of CKD-374 5 mg in healthy volunteers.

NCT ID: NCT03858504 Completed - Clinical trials for Enthesitis Related Arthritis

Yoga Versus Home Exercise Program in Children With Enthesitis Related Arthritis

Start date: July 31, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effectiveness of different exercises programs as 'Yoga' and 'Home Exercise' in Enthesitis Related Arthritis.

NCT ID: NCT03855007 Completed - Clinical trials for Arthritis, Rheumatoid

The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

This study is designed to observed prospectively the efficacy and safety of 6 months treatment of iguratimod alone, or with methotrexate (MTX), hydroxychloroquine (HCQ) and prednisone step by step on Chinese rheumatoid arthritis (RA) and early rheumatoid arthritis (ERA) patients who were naïve or shown insufficiency response or intolerance to DMARDs. If volunteered, patients who completed the 6-month study can continue to follow our plans for 24 months.

NCT ID: NCT03852888 Completed - Clinical trials for Rheumatoid Arthritis

Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients

MetU
Start date: November 14, 2018
Phase: N/A
Study type: Interventional

Methotrexate is a key treatment for inflammatory rheumatism. Therapeutic compliance with methotrexate is difficult to measure because of a lack of objective testing; however, therapeutic compliance is essential for the proper management of a patient. The objective is to characterize the kinetics of elimination of methotrexate and its main metabolite7-OH-methotrexate for observant patients according to treatment (dosage, administration) and patient characteristics. Once this kinetics is characterized, it will be considered as a comparison reference to identify non-observant patients that is to say having concentrations lower than the lower bound of the confidence interval of the observed concentrations.

NCT ID: NCT03852355 Completed - Clinical trials for Rheumatoid Arthritis

the Effectiveness of 3rd Occipital Radiofrequency Versus Systemic Steroid in Headache Management in Rheumatoid Arthritis

Start date: February 25, 2019
Phase: N/A
Study type: Interventional

Rheumatoid arthritis is a common type of autoimmune arthritis that is characterized by inflammation of the synovial membranes. Even though any joint can be affected by the disease, cervical spine is often affected, and cervical pain is reported by 40-88% of RA patients, Cervical spine involvement is a feature of long-lasting disease, where atlantoaxial impaction with odontoid process vertical subluxation through the foramen magnum being one of the greatest and dangerous complications

NCT ID: NCT03850392 Completed - Cryotherapy Effect Clinical Trials

Anti Inflammatory Effects of Local Cryotherapy in Knee Arthritis

ALGGAR
Start date: February 12, 2013
Phase: N/A
Study type: Interventional

47 patients with non-septic knee arthritis were treated by local ice (30 min) or cold CO2 (2 min) twice at an 8 hour-interval for 1 day. The synovial fluid was collected just before the first cold application then 24 hours later. Cytokine, VEGF, NF-kB, PG-E2 levels were assessed in the synovial fluid before/after treatment. Contralateral arthritic knees were used as paired controls when possible.

NCT ID: NCT03840785 Completed - Clinical trials for Rheumatoid Arthritis (RA)

Inflammatory Arthritis and Tango

IATANGO
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

The hypothesis is that pleasure brought by argentine tango practice would increase total physical activity of patients with chronic inflammatory arthritis.