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Arthritis clinical trials

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NCT ID: NCT01078116 Completed - Clinical trials for Rheumatoid Arthritis

Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)

HEOR
Start date: November 2007
Phase: N/A
Study type: Observational

Evaluation of Health Related Quality of Life (HRQL) is of a paramount importance in assessing the impact of rheumatoid arthritis on patients' health status, however when costs associated with rheumatoid arthritis are also taken into account, the information provided may lead to a more balanced view in analyzing the treatment of the disease. In accordance with the above, the main objective this study was to evaluate the impact of adalimumab treatment not only on patients' Health Related Quality of Life but also on the cost of the disease management. In order to accomplish this the study has been focused on: 1. Estimating the direct and indirect cost incurred by adalimumab treatment. 2. Measuring the Health Related Quality of Life of rheumatoid arthritis patients under adalimumab treatment. 3. Exploring the cost-utility relationship of rheumatoid arthritis patients treated with adalimumab by combining the Health Related Quality of Life of rheumatoid arthritis patients and direct as well as indirect costs due to RA. More specifically, data related to patients' Health Related Quality of Life and cost associated with rheumatoid arthritis will be recorded for one-year period, and collected at four subsequent visits: baseline, month 3, 6 and 12. The visit before starting treatment with adalimumab will be considered as baseline. This information was used to compare Health Related Quality of Life and cost data before and after adalimumab initiation and therefore identify the effect of adalimumab treatment in patients with rheumatoid arthritis.

NCT ID: NCT01078090 Completed - Clinical trials for Rheumatoid Arthritis

Effectiveness and Safety of Adalimumab in Rheumatoid Arthritis Patients in Routine Clinical Practice

Start date: April 2003
Phase: N/A
Study type: Observational

Observation of safety, tolerability and effectiveness of adalimumab (Humira) therapy in a large patient collective under everyday clinical conditions over a 5-year period.

NCT ID: NCT01077362 Completed - Clinical trials for Arthritis, Psoriatic

A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF Agents

Start date: March 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy (improvement of signs and symptoms) and safety of ustekinumab in patients with psoriatic arthritis.

NCT ID: NCT01077258 Completed - Clinical trials for Rheumatoid Arthritis

Efficacy and Safety of Adalimumab in Patients With Rheumatoid Arthritis in Routine Clinical Practice

Start date: April 2004
Phase: N/A
Study type: Observational

Observation of safety, tolerability and effectiveness of adalimumab (Humira) therapy in a large patient collective under everyday clinical conditions over 2 years.

NCT ID: NCT01076959 Completed - Clinical trials for Rheumatoid Arthritis

Drug Use Investigation for Humira® - All Patient Investigation for Rheumatoid Arthritis

Start date: June 2008
Phase: N/A
Study type: Observational

To clarify the following matters: - Unknown adverse reactions (especially clinically significant adverse reactions) - Incidence and conditions of occurrence of adverse reactions in the clinical setting - Factors that may affect the safety and effectiveness of Humira

NCT ID: NCT01076205 Completed - Clinical trials for Rheumatoid Arthritis

Safety and Effect on Quality of Life/Work Productivity of Humira in Patients With Rheumatoid Arthritis

AGIL
Start date: January 12, 2009
Phase:
Study type: Observational

The AGIL study was designed to evaluate the effectiveness and safety of adalimumab over 5 years in routine daily clinical practice in Germany, with a focus on the impact of therapy on employment-related outcomes.

NCT ID: NCT01075711 Completed - Clinical trials for Arthritis, Rheumatoid

Determine the Improvement in Activity Status/Quality of Life (QoL) of Patients With Rheumatoid Arthritis (RA) During Treatment With Lodotra (Prednisone)

LODOTRA
Start date: April 2009
Phase: N/A
Study type: Observational

Rheumatoid arthritis is the most common rheumatic disease with symptomatic morning stiffness which entails a quite essential restriction in the everyday life and in the life quality. This observational, uncontrolled, multicentric study is aimed to assess the improvement in the activity status or QoL of subjects with RA being treated with the Tempus tablet.

NCT ID: NCT01075477 Completed - Clinical trials for Rheumatoid Arthritis

An Observational Study on Patients With Rheumatoid Arthritis Treated With MabThera (Rituximab)

Start date: September 2009
Phase: N/A
Study type: Observational

This observational study will assess the execution, efficacy and safety of treatment with MabThera in patients with rheumatoid arthritis. Data from patients receiving MabThera according to local treatment guidelines will be collected for 29 months. Target sample size is 100-200 patients.

NCT ID: NCT01071798 Completed - Clinical trials for Rheumatoid Arthritis

An Observational Study on the Safety and Effectiveness of Rituximab in Patients With Severe Active Rheumatoid Arthritis

Start date: January 2010
Phase: N/A
Study type: Observational

This prospective observational study aims to evaluate safety, application and onset of effect of rituximab in clinical routine treatment of severe active rheumatoid arthritis during the first 6 months (in case of re-therapy: 12 months).

NCT ID: NCT01070121 Completed - Clinical trials for Rheumatoid Arthritis

Treatment Efficacy and Toxicity in Rheumatoid Arthritis Database and Repository

TETRAD
Start date: February 2010
Phase: N/A
Study type: Observational

To stimulate collaborative efforts of federal funding agencies, voluntary health agencies, professional organizations and industry partners to enable creation of a large, sustainable database and repository to better understand the molecular basis of treatment and rapidly accelerate translational research in RA.