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Arthritis clinical trials

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NCT ID: NCT01921478 Completed - Clinical trials for Rheumatoid Arthritis

A Retrospective, Observational Study of RoActemra/Actemra (Tocilizumab) in Clinical Practice in Patients With Rheumatoid Arthritis

Start date: August 2010
Phase: N/A
Study type: Observational

This retrospective, multi-centre, observational study will assess the daily practice patterns and outcomes of the management of rheumatoid arthritis in patients treated with RoActemra/Actemra (tocilizumab). No actual patient will be enrolled in this study; data will be collected from medical records.

NCT ID: NCT01919645 Completed - Clinical trials for Arthritis, Rheumatoid

Effectiveness and Safety of Physical Exercises in the Improvement of the Sleep Quality. Regarding Rheumatoid Arthritis

SRA
Start date: July 2012
Phase: N/A
Study type: Interventional

Physical exercise programs are effective and safe for the improvement of the sleep efficiency in patients with Rheumatoid Arthritis.

NCT ID: NCT01918267 Completed - Clinical trials for Rheumatoid Arthritis

U-Act-After: An Observational Study on Long-Term Efficacy of Tight Control RoActemra/Actemra (Tocilizumab) and/or Methotrexate in Patients With Early Rheumatoid Arthritis Who Have Participated in the U-Act-Early Study (ML22497)

Start date: April 10, 2012
Phase:
Study type: Observational

This non-interventional, observational, open-label multi-center follow-up study of patients from the U-Act-Early trial (ML22497) will evaluate the long-term efficacy and safety of starting tight control treatment with RoActemra/Actemra (tocilizumab) and/or methotrexate in patients early in the disease followed by treatment according to standard of care in routine clinical practice in a three year follow-up, independently of what treatment the patient will be receiving.

NCT ID: NCT01913080 Completed - Clinical trials for Rheumatoid Arthritis

The Health Log: A Randomized Clinical Trial

Start date: September 2013
Phase: N/A
Study type: Interventional

The goal of the present study is to determine if a health management tool improves self-efficacy, satisfaction with the doctor's visit, and agreement of the statement "How satisfied are you that your concerns were addressed during your clinic visit today" over time.

NCT ID: NCT01911234 Completed - Clinical trials for Rheumatoid Arthritis

Clinical Efficacy of TNF-Kinoid in Patients With Rheumatoid Arthritis

Start date: September 2013
Phase: Phase 2
Study type: Interventional

The safety and immunogenicity of the TNF-Kinoid (TNF-K) have been evaluated in a phase II clinical study conducted in subjects with Rheumatoid arthritis. Preliminary results of clinical efficacy are promising. The principal aim of the present study is to confirm the clinical efficacy of the TNF-K in subjects with Rheumatoid arthritis in whom treatment with methotrexate is not working anymore. Subjects who have never been treated with anti-TNFα monoclonal antibodies will be enrolled in this trial. In addition, the immune responses and the safety elicited by TNF-K will also be evaluated.

NCT ID: NCT01909427 Completed - Clinical trials for Rheumatoid Arthritis

An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Start date: June 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of CNTO6785 in participants with active rheumatoid arthritis (RA) despite methotrexate (MTX) therapy.

NCT ID: NCT01906177 Completed - Clinical trials for Rheumatoid Arthritis

A Prospective Munti-center Study on VANGUARD™ PS Total Knee Replacement System

Start date: July 2012
Phase:
Study type: Observational

The primary objectives of this pilot clinical study include: - Evaluate clinical outcomes and quality of life on patients who received Vanguard PS Total Knee in Korean population - Evaluate safety of Vanguard PS Total Knee in Korean population

NCT ID: NCT01905319 Completed - Epidemiology Clinical Trials

Juvenile Idiopathic Arthritis in Children in Estonia.

Start date: January 1998
Phase:
Study type: Observational

Aims of the study: - to study the incidence rate of juvenile idiopathic arthritis (JIA) and it's clinical subtypes in Estonia for the years 1998-2000; - to examine the course and short-term clinical outcome of JIA. Method: a prospective population-based study carried on in 14 counties of Estonia

NCT ID: NCT01904292 Completed - Clinical trials for Juvenile Idiopathic Arthritis

A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis

Start date: August 15, 2013
Phase: Phase 1
Study type: Interventional

This open-label, multicenter study will evaluate the pharmacokinetics, pharmacodynamics, and safety of subcutaneously administered tocilizumab in participants with Systemic Juvenile Idiopathic Arthritis (sJIA). Participants with body weight less than (<) 30 kilograms (kg) will receive subcutaneous (SC) tocilizumab dose every 2 weeks (Q2W) and participants with body weight greater than or equal to (>=) 30 kg will receive weekly (QW), for 52 weeks. Tocilizumab was administered every 10 days until pre-planned interim analysis was performed and changed to Q2W in participants with body weight <30 kg.

NCT ID: NCT01904279 Completed - Clinical trials for Juvenile Idiopathic Arthritis

A Study of Subcutaneously Administered RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular-Course Juvenile Idiopathic Arthritis

Start date: July 2013
Phase: Phase 1
Study type: Interventional

This open-label, multicenter study will evaluate the pharmacokinetics, pharmacodynamics and safety of subcutaneously administered RoActemra/Actemra (tocilizumab) in patients with polyarticular-course juvenile idiopathic arthritis. Patients will receive RoActemra/Actemra subcutaneously every 2 or 3 weeks for 52 weeks.