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Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia — ARIAA  

Arthritis Clinical Trial

Official title:
Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia (ARIAA)

Clinical Trial Summary

This is a randomised double-blinded placebo-controlled multi centre study in 98 patients with ACPA positive arthralgia. The study is composed of 2 arms with a 1:1 randomisation at baseline: Treatment phase will be 6 months. Group 1: Abatacept s.c. 125 mg weekly for 6 months vs. Group 2: Placebo s.c. for 6 months. After 6 months both groups will run into the follow up period for another 12 months up to month 18. Patients developing arthritis will be treated according to local guidelines.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02778906
Study type Interventional
Source University of Erlangen-Nürnberg Medical School
Contact
Status Completed
Phase Phase 3
Start date November 2014
Completion date December 2019
View Details
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