Arteriovenous Malformations Clinical Trial
Official title:
Sonography-guided Resection of Brain Mass Lesions: a Prospective, Single Arm Clinical Trial
Objective of the study is to determine possibilities of intraoperative sonography in detecting of various brain mass lesions, assessing extent of their resection and define indications to use ultrasound-guided needle or ultrasound wire-guided port.
Intraoperative sonography is usially used in neurooncology to detect brain tumors and exclude their remnants. A few studies describe it's usage while removing hematomas or vascular malformations. Ultrasound is the only method allowing to observe brain tissue in real time. It is chip and doesn't violate surgical workflow. Main disadvantages of sonography are lengthy learning curve and poorer image quality compared to magnetic resonance imaging. Novel acoustic coupling fluid, contrast-enhanced ultrasound and elastography expanded it's effectiveness. Meanwhile problems of locating of isoechogenic lesions with poor margins and elimination of artefacts are steel actual. Objective of the study is to determine possibilities of intraoperative sonography in detecting of various brain mass lesions, assessing extent of their resection and define indications to use ultrasound-guided needle or ultrasound wire-guided port. A surgeon will intraoperatively locate mass lesion and assess extent of it's resection with sonography. Ultrasound scanning will be performed through the same surgical approach or at a distance through enlarged craniotomy, periodically or permanently. To facilitate approach to subcortical and deep small mass lesions ultrasound-guided needle or ultrasound wire-guided port will be used. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03306836 -
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2
|
N/A | |
| Recruiting |
NCT03306823 -
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 1
|
N/A | |
| Completed |
NCT01347307 -
Stereotactic Body Radiotherapy for Spine Tumors
|
N/A | |
| Recruiting |
NCT02042326 -
Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations
|
Phase 2 | |
| Recruiting |
NCT05477680 -
Intraoperative Brain Shift Calculation Study
|
N/A | |
| Recruiting |
NCT05484219 -
Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations
|
N/A | |
| Completed |
NCT03656211 -
Fertility After Diagnosis and Management of Acquired Uterine Arteriovenous Malformation
|
||
| Completed |
NCT04246125 -
Patient Skin Dose in Interventional Radiology
|
||
| Recruiting |
NCT02879071 -
Long Term Follow-up After Embolization of Brain Arteriovenous Malformations
|
||
| Terminated |
NCT01801488 -
Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm
|
N/A | |
| Recruiting |
NCT06259292 -
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
|
||
| Recruiting |
NCT02098252 -
Treatment of Brain AVMs (TOBAS) Study
|
N/A | |
| Completed |
NCT02378883 -
Apollo™ Onyx™ Delivery Microcatheter Post Market Safety Study
|
N/A | |
| Completed |
NCT00783523 -
Influence of MMP on Brain AVM Hemorrhage
|
Phase 1 | |
| Recruiting |
NCT05276934 -
Brain Imaging After Non-traumatic Intracranial Hemorrhage (SAVEBRAINPWI)
|
||
| Recruiting |
NCT03031873 -
Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations
|
N/A | |
| Withdrawn |
NCT02079818 -
Visceral Artery Aneurysm Embolization by the Penumbra Ruby™ Coil System
|
Phase 4 | |
| Completed |
NCT01381952 -
Image Quality and Radiation Dose in Angiography
|
N/A | |
| Active, not recruiting |
NCT05418816 -
SelfWrap-Assisted Arteriovenous Fistulas
|
N/A | |
| Active, not recruiting |
NCT03559556 -
Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning
|
Early Phase 1 |