Arteriovenous Malformation Clinical Trial
Official title:
Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery: A Randomized Controlled Study
The purpose of this study is to determine effect of combined medication of sufentanil and dexmedetomidine in patient controlled analgesia after neurosurgery.
Sufentanil is a classical drug for postoperative analgesia. Dexmedetomidine is a commonly used α2-adrenergic receptor, and it helps provide sedation, analgesia and inhibition of sympathetic activation. The investigators propose to recruit 120 patients who is undergoing the arteriovenous malformation embolism operation in department of Neurosurgery. Patients will be randomly divided into 4 groups(control group, sufentanil and low dexmedetomidine dose group, sufentanil and middle dexmedetomidine dose group, sufentanil and high dexmedetomidine dose group), then the investigators select post-operative records to determine whether dexmedetomidine can take a positive role in neurosurgical analgesia. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00603694 -
Hippocampal Radiation Exposure and Memory
|
N/A | |
| Completed |
NCT00389935 -
Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding
|
Phase 2 | |
| Recruiting |
NCT02625389 -
Evaluation of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular Embolization.
|
Phase 4 | |
| Active, not recruiting |
NCT02445430 -
Genetics of Arteriovenous Malformations
|
||
| Completed |
NCT00972790 -
Scalp Nerve Blocks for Post-Craniotomy Pain
|
N/A | |
| Completed |
NCT00001364 -
Evaluation and Treatment of Patients Spinal Blood Vessel Abnormalities
|
N/A | |
| Recruiting |
NCT02496013 -
Clinical Translation of a Novel Albumin-Binding PET Radiotracer 68Ga-NEB
|
Phase 1 | |
| Completed |
NCT03269734 -
Evaluation of the Accuracy of the Vessel Navigator Tool for Catheterization of Supra-aortic Vessels - ARCHIBALD
|