Arterial Stiffness Clinical Trial
Official title:
Advanced Approach to Arterial Stiffness (AAA Study - Triple A Study)
The aim of the 3A Study is to assess the role of MetS on the arterial mechanics and vascular health in different age groups using the Cardio Ankle Vascular Index (CAVI) of the Vasera system and the "classic" carotid-femoral Pulse Wave Velocity (PWV).
Hypothesis The aim of thie 3A study is to assess the role of MetS on the arterial mechanics
and vascular health in different age groups using the Cardio Ankle Vascular Index (CAVI) of
the Vasera system and the "classic" carotid-femoral Pulse Wave Velocity (PWV).
STUDY OBJECTIVES
1. Objectives Primary Objective: Assess the influence of MetS on CAVI values (primary study
endpoint) in 3 different age groups (40-54, 55-69, 70-85 years) of a European
population.
2. Secondary Objectives
- Establish the CAVI values in a European population according to the clusters of
(MetS) components i.e. cardiovascular risk factors: abdominal obesity, high
triglycerides, low HDL cholesterol, elevated blood pressure (BP), systolic or
diastolic, and elevated fasting glucose (and diabetes), as well as tobacco smoking.
- Assess the correlation between CAVI and the carotid-femoral PWV in the full
population and in each age group; and compare the impact of MetS and its components
on both the CAVI and PWV
- To establish, the relationship between cardiovascular risk factors and the
evolution of arterial stiffness as evaluated by CAVI and carotid-femoral PWV over a
2-year follow-up period.
- To assess changes and predictive value of CAVI on organ damages and CV events
during the follow-up period.
- To assess 24h ABPM and its correlations and variations with the CAVI and PWV in
patients with MetS and/or its different components.
This is a multinational European prospective longitudinal study.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06133634 -
Fisetin to Improve Vascular Function in Older Adults
|
Phase 1/Phase 2 | |
| Completed |
NCT05872139 -
Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging
|
N/A | |
| Recruiting |
NCT05095688 -
Relationship Between Adipose Tissue Distribution and Arterial Stiffness in HFpEF
|
||
| Recruiting |
NCT04558450 -
Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN)
|
N/A | |
| Not yet recruiting |
NCT05943457 -
Vitamin K2 Supplementation in Adult Episodic Migraine
|
N/A | |
| Not yet recruiting |
NCT04900610 -
The Effect of Vitamin K2 Supplementation on Arterial Stifness and Cardiovascular Events in PEritonial DIAlysis
|
N/A | |
| Completed |
NCT02226055 -
An Investigation Into the Cardiovascular Risk and Aetiology of CKDu in Sri Lanka
|
N/A | |
| Completed |
NCT01559896 -
Egg Protein Hydrolysate and Vascular Function
|
N/A | |
| Completed |
NCT04049162 -
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
|
N/A | |
| Not yet recruiting |
NCT06440369 -
Physical Activity and Cardiovascular Risk
|
N/A | |
| Completed |
NCT05537246 -
The Relationship Between Arterial Stiffness and Hemodynamic Responses in Patients With Spinal Anesthesia
|
||
| Completed |
NCT06151054 -
Relationship Between Aortic Parietal Inflammation on 18F-FDG PET Scan and Arterial Stiffness as a Function of Age
|
||
| Completed |
NCT02218268 -
Arterial Stiffness in Type I Diabetes Mellitus
|
N/A | |
| Completed |
NCT00547040 -
Arterial Stiffness and Calcifications in Incident Renal Transplant Recipients
|
||
| Completed |
NCT02821780 -
CADASIL Disease Discovery
|
||
| Completed |
NCT05719090 -
Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Exercise on Indices of Arterial Stiffness
|
N/A | |
| Completed |
NCT04549324 -
Sleep Apnea, Coronary Atherosclerosis and Heart Failure in Diabetes Patients With Nephropathy
|
||
| Completed |
NCT05022498 -
Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
|
N/A | |
| Completed |
NCT03415880 -
Light Intensity Physical Activity Trial
|
N/A | |
| Completed |
NCT03560804 -
Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two Drugs
|
N/A |