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NCT ID: NCT04721522 Recruiting - ART Clinical Trials

The Impact of Endometrial Compaction on Assisted Reproductive Technology Outcome

Start date: January 29, 2021
Phase:
Study type: Observational

Absence of endometrial compaction on the day of ET has adverse effects on success of ART outcome.

NCT ID: NCT04268563 Recruiting - Infertility Clinical Trials

Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

Start date: January 10, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Investigators will evaluate and compare the efficacy of Sitagliptin/Metformin to metformin and sitagliptin on gdf9 and bmp15 gene expression on PCOS patients undergoing intracytoplasmic sperm injection(ICSI).

NCT ID: NCT03833869 Recruiting - ART Clinical Trials

Assisted Hatching in Frozen Blastocysts

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The current study aims to assess the effect of assisted hatching on the implantation rate of frozen blastocytes.

NCT ID: NCT03832699 Recruiting - ART Clinical Trials

Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The current trial is intended to assess the efficacy of oral versus vaginal progesterone for luteal support in frozen IVF cycles.

NCT ID: NCT03804294 Recruiting - ART Clinical Trials

Effect of Vitamin D on Outcome of Assisted Reproductive Technology(ART);

ART
Start date: November 28, 2018
Phase:
Study type: Observational

Vitamin D has many biological functions. Vitamin D receptors are widely distributed in the male and female reproductive system. Animal experiments have shown that vitamin D deficiency can affect hormone synthesis and gamete formation, reduce sperm motility, and may be related to diseases such as PCOS and endometriosis. Population studies suggest that vitamin D may be related to androgen levels and sperm quality, but whether vitamin D affects the outcome of assisted reproduction is controversial and inconclusive. This study intends to explore whether vitamin D affects the outcome of assisted reproduction through a large sample cohort study.

NCT ID: NCT03680053 Recruiting - Infertility Clinical Trials

Comparison of the Live Birth Rate Between the PPOS and the GnRH Antagonist Protocol in Patients Undergoing IVF

Start date: April 10, 2020
Phase: N/A
Study type: Interventional

A randomized comparison of the live birth rate between the progestin-primed ovarian stimulation protocol and the gonadotrophin releasing hormone antagonist protocol in patients undergoing in vitro fertilization Research question Does the live birth rate of the progestin-primed ovarian stimulation protocol comparable with the GnRH antagonist protocol for patients undergoing IVF? Design This is a randomized controlled trial. Research plan Population: Infertile women who have medical indication for IVF will be recruited for study if they fulfil the selection criteria. Intervention: Women will receive oral dydrogesterone 20mg daily from Day 3 till the day of ovulation trigger. Comparator: Women will receive antagonist (Cetrorelix 0.25mg) once subcutaneously daily from day 6 of ovarian stimulation till the day of the ovulation trigger. Outcomes: The primary outcome is the live birth rate the first FET. Ovarian stimulation, egg retrieval, embryos frozen and frozen embryo transfer will be performed according to the standard operating procedures of the centres.

NCT ID: NCT03650829 Recruiting - ART Clinical Trials

IVF Offspring Born in Guangzhou

IVF-BIG
Start date: February 1, 2012
Phase:
Study type: Observational

The IVF Offspring Born in Guangzhou Cohort Study (IVF-BIG) was established to investigate the short- and long-term effects of exposure in early life on the health of mothers and offspring in Guangzhou, China. Data are collected regarding assisted reproductive technology (ART), environmental, occupational and lifestyle exposures as well as health outcomes in their later life. Biological samples including blood and tissue samples are also collected from participants.

NCT ID: NCT03421314 Recruiting - HIV Clinical Trials

Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment.

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of zinc gluconate and/or selenium yeast supplementation during six months on clinical (glucose, cholesterol, triglycerides, bone mineral density and body composition) and immunological (oxidative stress, CD4+ count and pro-inflammatory cytokines) parameters in a population with HIV diagnosis on antiretroviral treatment.

NCT ID: NCT01963819 Recruiting - Infertility Clinical Trials

Therapeutic Endometrial Biopsy

Start date: January 2014
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the potential benefits in implantation, clinical pregnancy and live birth rates by an endometrial biopsy prior to an IVF/ICSI treatment. Including a follow up on possible pregnancy complications and data on children at birth. Further it is planned to aspirate secretions from the uterus and take blood samples during the treatment, which presumably can provide information about the mechanisms underlying the possible effect of the treatment.