The Study of EIT-guided Ventilation Strategy on ARDS Patients

ARDS Clinical Trial

Official title:

The Study of EIT-guided Ventilation Strategy on ARDS Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04734340
• Other study ID #: EIT-RCT
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2021
• Est. completion date: June 1, 2023

Study information

• Verified date: January 2021
• Source: Peking Union Medical College Hospital
• Contact: Yun Long
• Phone: 13911608699
• Email: ly_icu[@]aliyun.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is a clinical randomized controlled study.The objective of this study is to compare the prognosis of patients with ARDS between eit-v / q-oriented individualized ventilation strategy and traditional lung protection ventilation strategy, and to establish the demonstration application of eit-v / q-oriented ventilation strategy in ARDS

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: June 1, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

1. According to ARDS Berlin standard, ARDS, PaO2 / FiO2 < 200mmhg, peep > 5cmh2o;

2. According to clinical judgment, lung recruitment therapy is needed due to hypoxemia;

3. The subjects or their families signed informed consent.

4. Admission to ICU was less than 72 hours;

5. The estimated duration of mechanical ventilation was more than or equal to 48 hours;

6. Age = 18 years old and = 80 years old;

Exclusion Criteria:

1. The patients with heart implants could not be monitored by EIT;

2. Patients or their families refused to participate in the study;

3. Hypernatremia

Related Conditions & MeSH terms

• ARDS
• Pulmonary Perfusion

Intervention

Procedure:
• EIT-guided PEEP setting
Ventilator parameter setting by EIT
• ARDS-net PEEP setting
Ventilator parameter setting according to ARDS-net table

Locations

Country	Name	City	State
China	Peking Union Medical College Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking Union Medical College Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	ventilation free days		1 Day
Secondary	28-day mortality		28 days