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Effects of Sedation on Transpulmonary Pressure and Lung Homogenous — ARDS  

ARDS Clinical Trial

Official title:
Effects of Sedation on Transpulmonary Pressure and Lung Homogenous of ARDS Patients

Clinical Trial Summary

The acute respiratory distress syndrome (ARDS) is characterized by severe respiratory failure. Open Lung and Lung Protective Strategy have been proved to improve mortality of ARDS patients. Preserving spontaneous breathing (SB) is good for inflating the lung lobe near diaphram during mechanical ventilation, however, strong respiratory drive could generate more transpulmonary pressure in ARDS patients, which increase the stress and strain in injured lung. Nonetheless, it's not clear if sedative has any effects on transpulmonary pressure of ARDS patients.The purpose of this study is to investigate the effects of sedation on transpulmonary pressure of ARDS patients.

Clinical Trial Description

Further study details as provided by Nanjing Zhong-da Hospital, School of Medicine, Southeast University ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03237806
Study type Interventional
Source Southeast University, China
Contact
Status Completed
Phase N/A
Start date May 31, 2015
Completion date March 18, 2018
View Details
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