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Appetite Regulation clinical trials

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NCT ID: NCT01877460 Completed - Health Clinical Trials

Sodium Alginate in Chocolate Milk, Satiety and Glycemic Control

Start date: January 2012
Phase: N/A
Study type: Interventional

This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men. The findings of this study will illustrate whether the addition of sodium alginate to chocolate milk will improve the glycemic properties of chocolate milk and will potentiate its satiating characteristics. This study will also elucidate whether sodium alginates, incorporated into chocolate milk, will influence glycemia, appetite sensations and food intake in a dose-dependent manner. It is hypothesized that there will be a synergy between milk and sodium alginate beyond either alone. When combined with milk components, sodium alginate is expected to improve glycemia and induce satiety more than does either milk alone or alginate alone.

NCT ID: NCT01644539 Completed - Appetite Regulation Clinical Trials

Brain Activity and Hormonal Changes During Food Administration

Start date: July 2011
Phase: N/A
Study type: Interventional

The amount and kind of food which is ingested influences the regulation of meal size. Neural signals from the gastrointestinal tract travel via the vagus nerve to the brainstem and thalamus, which projects to the rest of the brain, in particular the hypothalamus, amygdala and primary sensory cortices. In neuroimaging studies in which the stomach was distended with a gastric balloon activation was observed in the right insula, left posterior amygdala, left posterior insula, left inferior frontal gyrus and anterior cingulate cortex. So far, no study has examined the effects of the ingestion or infusion of a food on the brain. In addition to neural signals, hormonal signals are important for meal termination. Hormones like insulin, ghrelin and cholecystokinin interact with gastric as well as sensory signals in the process of satiation, which ultimately leads to meal termination. The aim of this study is to investigate the interaction between food administration, hormone responses and brain responses. To this end an oral or intra-gastric load will be administered while measuring brain activity (functional magnetic resonance imaging) and hormone concentrations. Subjects will participate in one trainings session and in three functional magnetic resonance imaging (fMRI) sessions (35-min fMRI scan). A training session will take 40-minutes and consists of placing a naso-gastric tube and ingesting 500 ml of chocolate milk orally. The fMRI sessions will consist of three conditions: in condition one (A) 500ml of chocolate milk will be administrated orally. In condition two (B) and three (C) an intra-gastric load of 500 ml is administrated.

NCT ID: NCT01259895 Completed - Obesity Clinical Trials

Effects of Time of Sleep Restriction in Obesity

Start date: February 2009
Phase: N/A
Study type: Observational

The purpose of this study is to determine the effect of different time of sleep restriction on control of food intake and metabolism of obese and normal subjects.

NCT ID: NCT01240018 Completed - Obesity Clinical Trials

ProSat - Long Term Effect of Probiotics on Satiety

ProSat
Start date: September 2009
Phase: N/A
Study type: Interventional

The aim of the ProSat study is to examine the effects of a probiotic capsule containing Lb. Casei on subjective appetite sensation, ad libitum energy intake, and appetite hormone response in a single meal test and to determine whether the acute effects persist after daily supplementation of the probiotic capsule.

NCT ID: NCT00912197 Completed - Obesity Clinical Trials

Effect of Oligofructose on Appetite in Overweight Subjects

Start date: June 2009
Phase: N/A
Study type: Interventional

This study seeks to look into the effects of oligofructose supplementation on appetite, energy intake, and body weight and body composition in overweight subjects. Compared to a placebo product (cellulose) oligofructose is hypothesised to suppress hunger and thereby reduce food intake moderately leading to a decrease in body weight.

NCT ID: NCT00826761 Completed - Obesity Clinical Trials

ProSat - Effect of Probiotics on Satiety

ProSat
Start date: January 2009
Phase: N/A
Study type: Interventional

The aim of the ProSat study is to examine the effects of a probiotic capsule containing one of two doses (low and high dose) of Lb. Casei on subjective appetite sensation, ad libitum energy intake, and appetite hormone response in a single meal test and to determine whether the acute effects persist after daily supplementation of the probiotic capsule.

NCT ID: NCT00776256 Completed - Appetite Regulation Clinical Trials

Effects of Oligofructose and Barley on Satiety and Energy Intake

Start date: February 2007
Phase: N/A
Study type: Interventional

The effect of beta-glucan or fructo-oligosaccharide or their combination in bars on satiety and food intake was tested by supplying these bars on two consecutive days.