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Appendicitis clinical trials

View clinical trials related to Appendicitis.

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NCT ID: NCT04860570 Recruiting - Clinical trials for Surgical Site Infection

Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?

sSSI-2RWEPs
Start date: October 25, 2024
Phase:
Study type: Observational

This study aims to evaluate the utility of double-ring wound-edge protectors to prevent the development of superficial surgical site infections after open appendectomy.

NCT ID: NCT04838379 Completed - Appendicitis Clinical Trials

Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The current study aimed to assess the efficacy of Dexmedetomidine (DEX) and Dexamethasone as an adjuvant to ultrasound guided TAP and RS block to prolongation of postoperative analgesia and better pain control in children undergoing laparoscopic surgeries

NCT ID: NCT04806789 Recruiting - Children, Only Clinical Trials

Plasma Sodium: a Predictor of Perforation in Acute Appendicitis. (The NAP-study)

Start date: June 1, 2021
Phase:
Study type: Observational

This clinical prospective diagnostic accuracy study assesses plasma sodium concentration using blood gas analysis at the emergency department in children, age 1-15 years, with suspected acute appendicitis. The overall assumption is that using plasma sodium as a biomarker, a cut-off value of <136 mmol/L will differentiate perforated from non-perforated acute appendicitis. In addition, traditionally used clinical diagnostic variables as well as radiology used in the diagnosis of acute appendicitis will also be obtained. Histopathology will be used to define if the appendix is perforated or not.

NCT ID: NCT04803422 Recruiting - Clinical trials for Complicated Appendicitis

Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis.

PIPA
Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The PIPA trial is a prospective, multicentre, cluster randomized cluster crossover non-inferiority study. We aim to test whether a three-day postoperative course of per oral antibiotics is non-inferior to a three-day postoperative course of intravenous antibiotics as standard care after laparoscopic surgery for complicated appendicitis in regards to the risk of postoperative intraabdominal abscess formation within 30-days

NCT ID: NCT04791657 Completed - Appendicitis Acute Clinical Trials

Outcome of Elderly Patients With Appendicitis

Start date: January 1, 2017
Phase:
Study type: Observational

This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

NCT ID: NCT04786041 Completed - Covid19 Clinical Trials

the Impact of COVID-19 Pandemic on the Incidence and Outcome of Complicated Appendicitis

Start date: March 1, 2020
Phase:
Study type: Observational

During the COVID-19 pandemic, we noticed a rise in complicated appendicitis cases presenting to our medical center. We collected objective data on all patients admitted to the surgical department with appendicitis during February 2020 - March 2020 compared to the same 2 month period in 2019, to understand the pandemic's affect on the rate of complications of acute appendicitis.

NCT ID: NCT04755179 Recruiting - Appendicitis Clinical Trials

Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population

CAPP
Start date: August 12, 2019
Phase:
Study type: Observational

Aim of this study is to evaluate the effect of different treatment strategies on overall complications, health related-Quality of Life (hr-QOL) and costs among two subtypes of complex appendicitis in children (<18 years old). Main research questions: What is the difference in overall complications at three months between: Subgroup 1 (complex appendicitis without abscess/mass formation): Laparoscopic (LA) and open appendectomy (OA) Subgroup 2: (complex appendicitis with abscess/mass formation): Non-operative treatment (NOT) and direct appendectomy

NCT ID: NCT04753502 Completed - Clinical trials for Other Specified Complications of Pregnancy

Laparoscopic Treatment for Appendicitis During Pregnancy

Start date: September 1, 2005
Phase:
Study type: Observational

Acute appendicitis is the most frequent non-obstetric surgical emergency during pregnancy. The benefits of laparoscopy during pregnancy are well known, but complications can occur, and these can affect both the mother and/or the foetus. Objective: Evaluate results of laparoscopic surgical treatment of acute appendicitis in pregnant women, to analyse the occurrence of adverse postoperative, obstetric and foetal outcomes Methods: Retrospective cohort single-centred observational study on pregnant women with a preoperative diagnosis of acute appendicitis,using computerized medical records' information of pregnant patients admitted to our institution between September 2005 and July 2020

NCT ID: NCT04751214 Completed - Appendicitis Acute Clinical Trials

New Technique For Laparoscopic Appendicectomy

Start date: January 2002
Phase:
Study type: Observational

Introduction: Appendectomy is one of the most frequent emergency surgical procedures, currently with a preference for laparoscopic management worldwide. Objective: To report a new laparoscopic appendectomy technique and its results. Material and methods: study of patients with a diagnosis of appendicitis who are managed laparoscopically. In a total 1063 patients, 148 were operated on with the Zaragoza technique during the period from January 2002 to December 2018. The technique consists of making a window in the appendicular base between the meso and the appendicular wall, two prolene or silk sutures are placed, and the cecal appendix is cut between the two sutures, finally the mesoappendix is sectioned with a harmonic scalpel or bipolar clamp.

NCT ID: NCT04748120 Terminated - Covid19 Clinical Trials

Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

This study evaluates operative and non-operative management of acute appendicitis (infection or inflammation of the appendix) and acute cholecystitis (inflammation/infection of the gallbladder) in patients with active mild to moderate COVID-19 infection. The hypothesis is that COVID+ patients with uncomplicated acute appendicitis or acute cholecystitis amendable to a laparoscopic procedure can have safe operative outcomes compared to those managed non-operatively.