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Apnea clinical trials

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NCT ID: NCT04120428 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Effects of Exercise on Obstructive Sleep Apnea Severity in Elderly

Start date: January 2020
Phase: N/A
Study type: Interventional

Obstructive sleep apnea syndrome (OSAS) is defined as a total cessation of upper airway flow for at least 10 seconds. OSAS is considered under diagnosed and it is assessed by a full-night sleep polysomnography. Continuous positive airway pressure (CPAP) is considered the first line treatment to OSAS, however physical exercise has emerged as an adjunct and/or alternative strategy to CPAP in OSAS patients.

NCT ID: NCT04093102 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Role of Biomarkers to Screen for Obstructive Sleep Apnea

Start date: October 1, 2019
Phase:
Study type: Observational

assess the relationship between obstructive sleep apnea and endocrine, inflammatory, and metabolic bio-markers in consecutively enrolled adult male patients with a clinical suspicion of obstructive sleep apnea.

NCT ID: NCT04018547 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Investigating a Wrist-sensor Oximeter to Screen for Sleep Apnoea.

Start date: September 17, 2019
Phase:
Study type: Observational

The primary study objective is to investigate sensitivity and specificity of a wrist sensor pulse oximeter (the Oxitone Medical Oxitone 1000M device) to screen for obstructive sleep apnoea. This study will involve thirty participants attending a sleep centre suspected of suffering from obstructive sleep apnoea (case finding screening). The secondary objective is to assess patient convenience with the screening procedure.

NCT ID: NCT03850353 Not yet recruiting - Dizziness Clinical Trials

Obstructive Sleep Apnea Syndrome (OSAS) and Dizziness

OSASDiz
Start date: April 1, 2019
Phase:
Study type: Observational

A total of 400 participants will be recruited: 200 patients with suspected OSAS will be recruited from the sleep clinic (OSAS group), 100 patients diagnosed with dizziness will be recruited from the ENT clinic (Dizziness group). In addition, 100 patients with no dizziness and no evidence for OSAS will be recruited from both the sleep clinic and the ENT clinic (controls). Informed consents will be completed by all participants. ). In order to assess the effect of treatment of OSAS on dizziness -patients with the diagnosis of OSAS will complete validated questionnaires regarding sleep, dizziness and eustachian tube function 3 months following initiation of treatment with CPAP

NCT ID: NCT03842618 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Asthma Outcomes in Children After Adenotonsillectomy

Start date: April 1, 2019
Phase:
Study type: Observational

The aim of the study is to assess the effect of adenotonsillectomy on level of asthma control in preschool children with obstructive sleep apnea.

NCT ID: NCT03788668 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Role of Hyoid Suspension With Barbed Reposition Pharyngoplasty in Management of Lateral Pharyngeal Wall Collapse in Obstructive Sleep Apnea Patients

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Aim of the study To determine the exact role of hyoid bone suspension surgery in splinting lateral pharyngeal wall in the era of the lateral pharyngoplasty

NCT ID: NCT03729895 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea Syndrome

Clinical Study of Customized Adjustable Oral in Treatment of Patients With Obstructive Sleep Apnea Syndrome

Start date: November 2018
Phase: N/A
Study type: Interventional

The oral appliances (OAs) are considered to be an effective treatment modality for snoring and various forms of obstructive sleep apnea syndrome (OSAS). They facilitate the displacement of the mandible anteriorly and widen the upper airway during sleep. Lateral cephalometry has been used for the two-dimensional evaluation of upper airway form with several limits.The purpose of present study is to investigate an accurate three-dimensional (3D) volume analyses with cone beam computed tomography (CBCT) scans to confirm the effects of OAs on the upper airway in patients with OSAS.The investigators aim to enroll twenty-four patients with mild,moderate or severe OSAS, intolerant to continuous positive air pressure therapy and rejection a surgical approach,who will be treated with adjustable customized OAs and evaluated with CBCT and polysomnography. Upper airway form was examined and the volume was measured in two different areas. Specific planes have been considered to match the data and calculate the benefit obtained with therapy.

NCT ID: NCT03568240 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea of Adult

Voice Acoustic Properties in People With Obstructive Sleep Apnea Syndrome (OSAS)

Start date: July 2018
Phase:
Study type: Observational

The aim of this study is to examine whether voice acoustic properties has an influence on sleep apnea. Sleep apnea syndrome is defined as a sudden stop of more than ten seconds multiple times during sleep. The syndrome is common especially among men and occurs in 2%-4% of the population aged 30-60. The syndrome diagnosis is performed by an ENT (Ear, Nose and Throat) physician. The diagnosis is based on evaluation of anatomical structures in the sound path (nose and throat, jaw, pharynx and oral cavity) and a Polysomnography (PSG) test which quantifies the number and duration of breathing pauses during night sleep and additional parameters that monitor sleep. The syndrome has many negative consequences for those who suffer from it, including fatigue , lack of concentration, hypertension, diabetes ,heart disease, stroke and even death. Therefore, early diagnosis is important.

NCT ID: NCT03546751 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Extracellular microRNA: Biomarkers of Endothelial Dysfunction in Obese Adolescents & Adults With Obstructive Sleep Apnea

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Using a prospective observational approach and a clinical trial design comparing the effectiveness of continuous positive airway pressure to diet and exercise, investigators plan to evaluate how obstructive sleep apnea (OSA) leads to endothelial dysfunction in adolescents and young adults and whether treatment of OSA can improve endothelial dysfunction. Concurrently, investigators will measure miR 92a/miR 210 levels in all subjects at baseline and following therapy to determine whether miR 92a/miR 210 levels reliably predict endothelial dysfunction in patients and responses to therapy.

NCT ID: NCT03514199 Not yet recruiting - Sleep Apnea Clinical Trials

Mediterranean-type Diet for Older Adults With Obstructive Sleep Apnea

MedOOSA
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The majority of the elderly present with sleep apnea and mortality is significantly higher in this group. Sleep apnea runs the risk of developing diseases, especially hypertension and cardiovascular disease, while the Mediterranean diet is associated with reduced risk. No study evaluated the effect of the Mediterranean diet on the apnea and hypopnea index in the elderly. Therefore, the present work intends to evaluate the effect of the intervention with the Mediterranean diet on the apnea-hypopnea index in the elderly with moderate sleep apnea. The hypothesis study is that the elderly with moderately severe sleep apnea under a Mediterranean-type diet will modify AHI in the short term, regardless of weight change, due to changes in body volume and ingestion, especially those related to body water.