Obesity Clinical Trial
Official title:
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome - COLOSS
It has been shown to date that obesity is associated with increased mortality and that weight loss significantly improves cardiovascular risk factors. Among patients receiving bariatric surgery, 30-90% have moderate to severe obstructive sleep apnea (OSA) syndrome. Given the strong associations between OSA and cardiometabolic comorbidities, this project is based on the hypothesis of a lower improvement of cardiovascular risk factors and a higher number of post-surgical complications in OSAS patients.
It has been shown to date that obesity is associated with increased mortality and that weight
loss significantly improves cardiovascular risk factors.
Bariatric surgery is now the most effective intervention for the long-term treatment of
obesity and its complications. Among patients receiving bariatric surgery, 30-90% have
moderate to severe obstructive sleep apnea (OSA) syndrome. The progressive loss of weight
contributes to the regression of the symptoms related to OSA. Observational studies have
shown that bariatric surgery can rapidly improve glycemic control and cardiovascular risk
factors with a significantly higher remission rate of hypertension and dyslipidemias than in
the non-surgical group. Given the strong associations between OSA and cardiometabolic
comorbidities, this project is based on the hypothesis of a lower improvement of
cardiovascular risk factors and a higher number of post-surgical complications in OSAS
patients.
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