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Aortic Valve Stenosis clinical trials

View clinical trials related to Aortic Valve Stenosis.

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NCT ID: NCT05991271 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Venus-Vitae Pivotal Study Smart-Align Study

Start date: October 31, 2023
Phase: N/A
Study type: Interventional

The purpose is to evaluate the safety, effectiveness and performance of Venus-Vitae Transcatheter Heart Valve System in patients with severe aortic stenosis.

NCT ID: NCT05989074 Not yet recruiting - Clinical trials for Aortic Stenosis, Severe

All Women Comparing Self-expanding ALLEGRA Valve to Any Other Balloon-expandable Valve

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Study is aimed to demonstrate that the self-expandable Allegra TAVI system provides lower mean gradient assessed by TTE compared to balloon-expandable valve systems in a female patient population with symptomatic severe aortic stenosis

NCT ID: NCT05977257 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

VitaFlow® Transcatheter Aortic Valve Replacement System Pre-market Trial Long Term Follow Up (VITAL)

VITAL
Start date: July 30, 2023
Phase:
Study type: Observational

This study is an observational study to evaluate the long-term safety and effectiveness of the valve system.

NCT ID: NCT05895097 Not yet recruiting - Heart Failure Clinical Trials

Conventional Versus Left Bundle Branch Pacing in TAVI

Start date: June 15, 2023
Phase: N/A
Study type: Interventional

This randomized study compares the effects of conventional (right ventricular pacing in patients with LVEF ≥ 40% and cardiac resynchronization therapy in patients with LVEF < 40 %) versus left bundle branch pacing on left ventricular remodelling in patients with reduced left ventricular ejection fraction (< 50 %) that need permanent pacemaker implantation after transcatheter aortic valve implantation (TAVI).

NCT ID: NCT05889208 Not yet recruiting - Aortic Stenosis Clinical Trials

Prophylactic Permanent Pacemaker in Patients With Right Bundle Branch Block Undergoing Transcatheter Aortic Valve Implantation

TAVI-PACE
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the safety and outcome of prophylactic pacemaker implantation in patients with right bundle-branch block undergoing trans-catheter aortic valve (TAVI) implantation in patients with severe aortic stenosis and left ventricular ejection fraction.Participants will be randomized to: - Prophylactic pacemaker implantation prior TAVI - Conservative strategy

NCT ID: NCT05875675 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Effects of Pioglitazone in Calcific Aortic Valve Disease

Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized, comparative, clinical trial conducted by Wuhan Union Hospital that aims to evaluate the efficacy and safety of pioglitazone compared to placebo in patients with calcific aortic valve disease with mild aortic valve stenosis.

NCT ID: NCT05861648 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Folic Acid Supplementation in Calcific Aortic Valve Disease

Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized, comparative, clinical trial conducted by Wuhan Union Hospital that aims to evaluate the efficacy and safety of folic acid compared to placebo in patients with calcific aortic valve disease with mild aortic valve stenosis.

NCT ID: NCT05851209 Not yet recruiting - Aortic Stenosis Clinical Trials

Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

Start date: July 1, 2023
Phase:
Study type: Observational

Biomarkers and mechanisms in the progression of aortic valve stenosis are sometimes not sufficiently understood. The current project will take into account image morphological and immunological aspects that predict the development of hemodynamically relevant aortic valve stenosis in order to identify high-risk patients and to develop further therapeutic options.

NCT ID: NCT05847751 Not yet recruiting - Clinical trials for Severe Aortic Valve Stenosis

The Use of ACURATE Neo 2 Valve in Patients With Symptomatic Aortic Valve Stenosis

BSC07
Start date: January 2024
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to evaluate the ACURATE Neo2 in the Middle East population with severe, symptomatic aortic stenosis.

NCT ID: NCT05836311 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Single Perclose Escalation Technique for Vascular Closure in TAVR

Start date: July 19, 2023
Phase:
Study type: Observational

This study examines in the safety and efficacy of using a single Perclose escalation technique (SPET) using a single Perclose Proglide device to preclose and the need for a rescue device based on a control angiography at the end of the procedure, with a 6F femoral sheath.