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Clinical Trial Summary

Aortic valve disease is a progressive illness that varies from minor valve thickening lacking obstruction of blood stream to severe calcification and alteration of the valve leading to weakened leaflet motion. Aortic valve replacement is a usual operation but can be complicated by a small aortic annulus requiring the insertion of an aortic valve prosthesis. Prosthesis-patient discrepancy results in worse outcomes.


Clinical Trial Description

Prosthesis-patient discrepancy results in worse outcomes, including elevated left ventricular work, decreased left ventricular mass regression, and has also been linked with high mortality. Therefore, Aortic root posterior enlargement by autologous fixed pericardium to insert an Aortic valve prosthesis with size suitable to patient body surface area to avoid the previous worse outcome of patient prosthesis mismatch. In this study the investigators will try to identify the benefits of Aortic Root Enlargement in management of Small Aortic Annulus in Patients with severe valvular aortic stenosis ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03603483
Study type Interventional
Source Assiut University
Contact Mohamed mahmoud ahmed, Doctor
Phone 01008332462
Email mohamedmahmoudclinic@gmail.com
Status Not yet recruiting
Phase N/A
Start date January 15, 2019
Completion date March 30, 2019

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