Small Aortic Annulus - a New Solution to the Old Problem

Status Active, not recruiting

Clinical Trial Summary

In this prospective single-center study included 60 patients with a severe degenerative aortic stenosis and small aortic annulus (<21 mm) who underwent standard AVR with stented bioprosthesis (group 1, n=30) and aortic valve reconstruction using autologus pericardium (Ozaki procedure) (group 2, n=30)

Clinical Trial Description

Aortic valve replacement (AVR) in patients with a small aortic annulus is a challenging problem. Implantation of a small aortic valve sometimes leads to high residual gradients, despite a normally functioning prosthesis. Patients with a small aortic annulus, especially those with a large body surface area, are at higher risk of prosthesis-patient mismatch, which is associated with worse clinical outcomes and decreased survival. The purpose of this study was to compare the hemodynamic performance among the 2 management strategies (standard AVR with stented bioprosthesis and Ozaki procedure) in the context of a small aortic annulus (<21 mm) ;

Study Design

Related Conditions & MeSH terms

Aortic Valve Replacement

Clinical Trial Details

NCT number	NCT03258333
Study type	Observational
Source	The Federal Centre of Cardiovascular Surgery, Russia
Contact
Status	Active, not recruiting
Phase	N/A
Start date	February 18, 2017
Completion date	July 1, 2022

View Details

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