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The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose

Cardiac Surgery Clinical Trial

Official title:
The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose

Clinical Trial Summary

The overall research plan is to test the hypothesis that intraoperative treatment of hyperinsulinemic normoglycemic clamp (HNC) in cardiac surgical patients improves myocardial function and short-term outcomes compared with standard glucose management.

Clinical Trial Description

Specific Aim #1:To determine whether intraoperative use of HNC affords cardioprotective benefits measured by improved echocardiographic measures of myocardial function, serum markers of cardiomyocyte injury, and hemodynamic indices measured immediately (at end of surgery) and during the short-term (initial hospitalization). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01187329
Study type Interventional
Source The Cleveland Clinic
Contact
Status Completed
Phase N/A
Start date October 2010
Completion date December 2013
View Details
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