Clinical Characteristics, Management Patterns and Outcomes of Type A Aortic Dissection: A Sino-US Comparative Cohort Analysis

Aortic Dissection Clinical Trial

Official title:

Clinical Characteristics, Management Patterns and Outcomes of Type A Aortic Dissection: A Sino-US Comparative Cohort Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05409469
• Other study ID #: NanjingFirst AAD
• Status: Completed
• Start date: January 2012
• Est. completion date: December 2021

Study information

• Verified date: May 2022
• Source: Nanjing First Hospital, Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This study constructed a retrospective cohort study by retrospectively analyzing the data of all patients with aortic dissection from January 1, 2012 to December 31, 2021 from the Cardiovascular Disease Registration System of Jiangsu Province in China and the data of similar diseases in recent years from National Inpatient Sample database in the United States

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11550
• Est. completion date: December 2021
• Est. primary completion date: December 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1.Clinical diagnosis of type A Aortic Dissection

Exclusion Criteria:

1. age<18, age unknown,

2. diagnosis of aortic aneurysm, transfer out within 1 day,

3. unknown vital status at discharge;

4. unknown treatment type: cardioplegia, valve or cardiac repair only without aortic repair or two types of treatments on different days

Related Conditions & MeSH terms

• Aneurysm, Dissecting
• Aortic Dissection

Intervention

Procedure:
• surgery
surgery on patients with aortic dissection

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Xin Chen	China Medical University, China

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Baseline data of patients with type A aortic dissection was assessed by SPSS 17.0	Baseline data of patients with type A aortic dissection included gender, age,height, weight, past medical history, family history, hospital costs, etc.	from 2015 to 2019
Primary	The main efficacy indicators was assessed by SPSS 17.0.	The main efficacy indicators included surgical procedures, surgical outcome (postoperative bleeding, ICU stay, extubation time), perioperative complications (including infection, bleeding, neurological complications, cardic complications, renal insufficiency, etc.), and postoperative mortality.	from 2015 to 2019