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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05044494
Other study ID # 21MMHIS005e
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 2004
Est. completion date June 2020

Study information

Verified date May 2021
Source Mackay Memorial Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

From November 2004 to June 2020, there were more than 200 patients with acute TAAD patients who underwent aortic surgery at our hospital.Of all the patients in the study period, there were 34 patients (defined as study group) who sought for medical attention with symptoms for several days (median 5 days, range 3-7 days) or deferred aortic surgery several days later (median 3 days, range 2-7 days) even though acute TAAD was diagnosed on the same day when chest pain or back pain occurred. For reducing the selection bias, propensity score matching (PSM) was used to match the study group with the control group from all the patients treated at our hospital during the study period. Comparison between the two groups was performed.


Description:

From November 2004 to June 2020, there were more than 200 patients with acute TAAD patients who underwent aortic surgery at our hospital. The research protocol used in this study was approved by the institutional review board of MacKay Memorial Hospital (IRB number: 21MMHIS005e). Of all the patients in the study period, there were 34 patients (defined as study group) who sought for medical attention with symptoms for several days (median 5 days, range 3-7 days) or deferred aortic surgery several days later (median 3 days, range 2-7 days) even though acute TAAD was diagnosed on the same day when chest pain or back pain occurred. The mean age at presentation was 60.2 +/- 13.2 years (range 33.4~83.5 years). All the patients in the study group were divided into 3 groups: DP group (n=22) with acute TAAD diagnosis delayed by patient but received prompt aortic surgery; DD group (n=4) with acute TAAD diagnosis delayed by patient and received deferred aortic surgery; ID group (n=8) with acute TAAD diagnosis on the same day when the symptoms occurred but received deferred aortic surgery several days later. For reducing the selection bias, propensity score matching (PSM) was used to match the study group with the control group from all the patients treated at our hospital during the study period. Comparison between the two groups was performed.


Recruitment information / eligibility

Status Completed
Enrollment 68
Est. completion date June 2020
Est. primary completion date June 2020
Accepts healthy volunteers
Gender All
Age group 33 Years to 83 Years
Eligibility Inclusion Criteria: - the patients sought for medical attention with symptoms (chest pain, back pain or shortness of breath) for several days or deferred aortic surgery several days later although acute TAAD was diagnosed on the same day when chest pain or back pain occurred Exclusion Criteria: -

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
non-prompt surgery


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Mackay Memorial Hospital

Outcome

Type Measure Description Time frame Safety issue
Primary surgical mortality in-hospital death 2004-2020
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