Aortic Dissection Clinical Trial
— FFDAOfficial title:
Non Traumatic Aortic Dissection : Chain of Care and Pre-hospital Risk Factors, a Retrospective, Multicenter Study
NCT number | NCT04304443 |
Other study ID # | P/2019/453 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | March 1, 2020 |
Est. completion date | July 1, 2020 |
Background :
Time between symptoms onset and treatment initiation is crucial in Acute aortic dissection
(AAD). An anti-hypertensive treatment can be rapidly initiated before the arrival in
Emergency Department (ED). A better understanding of the chain of care between symptoms onset
and surgery could lead to a reduction of morbi-mortality. Our study have the objective to
describe the chain of care of patients with AAD in the ED.
Methods :
This is an observational, retrospective, multicenter study. Patients were detected with a
discharge of diagnostic of aortic dissection (ICD I71.0) in university medical center of
Besançon. Data collection : patients records in the 8 hospitals centers of the area
Franche-Comté.
Status | Recruiting |
Enrollment | 300 |
Est. completion date | July 1, 2020 |
Est. primary completion date | May 1, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria : - patients with age > 18 years - patients with the diagnosis of non traumatic acute aortic dissection - patients hospitalized in the university medical center Exclusion Criteria : - decision of withdrawal life support - patients that died without a diagnosis confirmation with Helical Computed Tomography (HCT), Magnetic Resonnance Imagery (MRI), TransEsophageal Echocardiography (TEE) or surgery/autopsy - AAD that were complications of coronarography or aortic surgery - lack of information - patient opposition to study participation |
Country | Name | City | State |
---|---|---|---|
France | CHU de Besançon | Besançon | |
France | Hôpital Nord Franche-Comté | Trévenans |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire de Besancon | Centre hospitalier de Dole, Centre hospitalier de Gray, Centre Hospitalier de Lons Le Saunier, Centre hospitalier de Pontarlier, Centre Hospitalier de Saint-Claude, Centre hospitalier de Vesoul, Hôpital Nord Franche-Comté |
France,
Axelsson C, Karlsson T, Pande K, Wigertz K, Örtenwall P, Nordanstig J, Herlitz J. A description of the prehospital phase of aortic dissection in terms of early suspicion and treatment. Prehosp Disaster Med. 2015 Apr;30(2):155-62. doi: 10.1017/S1049023X150 — View Citation
Booher AM, Isselbacher EM, Nienaber CA, Trimarchi S, Evangelista A, Montgomery DG, Froehlich JB, Ehrlich MP, Oh JK, Januzzi JL, O'Gara P, Sundt TM, Harris KM, Bossone E, Pyeritz RE, Eagle KA; IRAD Investigators. The IRAD classification system for characte — View Citation
Dixon M. Misdiagnosing aortic dissection: a fatal mistake. J Vasc Nurs. 2011 Dec;29(4):139-46. doi: 10.1016/j.jvn.2011.08.003. — View Citation
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators. Insights From the International Registry — View Citation
Harris KM, Strauss CE, Eagle KA, Hirsch AT, Isselbacher EM, Tsai TT, Shiran H, Fattori R, Evangelista A, Cooper JV, Montgomery DG, Froehlich JB, Nienaber CA; International Registry of Acute Aortic Dissection (IRAD) Investigators. Correlates of delayed rec — View Citation
Nazerian P, Giachino F, Vanni S, Veglio MG, Castelli M, Lison D, Bitossi L, Moiraghi C, Grifoni S, Morello F. Diagnostic performance of the aortic dissection detection risk score in patients with suspected acute aortic dissection. Eur Heart J Acute Cardio — View Citation
Pape LA, Awais M, Woznicki EM, Suzuki T, Trimarchi S, Evangelista A, Myrmel T, Larsen M, Harris KM, Greason K, Di Eusanio M, Bossone E, Montgomery DG, Eagle KA, Nienaber CA, Isselbacher EM, O'Gara P. Presentation, Diagnosis, and Outcomes of Acute Aortic D — View Citation
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Primary | Mortality rate | 30 days |
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