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Aortic Aneurysm clinical trials

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NCT ID: NCT00591968 Completed - Clinical trials for Abdominal Aortic Aneurysm

Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community

Start date: January 2008
Phase: N/A
Study type: Interventional

The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard of patient care throughout the world. Perhaps the safest and most cost effective mode of teleradiology today is telesonography. The current project attempts to determine the extent that telesonography improves the standard of care within a rural government-run primary clinic within the Dominican Republic. The work reported herein is intended to compare the use of telesonography to the current standard of sonographic examination (referral to government hospital 60km from target clinic). The study was conducted by randomly assigning 100 patients with clinical indications for sonographic examination into experimental and control groups. Following a 60-day implementation period, the following research questions will be addressed: 1) To what extent does the use of asynchronous telesonography increase the percentage of definitive diagnoses based on the total number of scans (definitive diagnoses / total number of scans)? 2) To what extent does the use of asynchronous telesonography increase the continuity of care for patients? 3) To what extent does the elapsed time between scanning and final radiological interpretation decrease with the use of asynchronous telesonography? This study will also look at the history of telemedicine / telesonography and its dissemination into the mainstream practice of medicine, explore training protocols that may be used to assist others to establish new telesonography programs in a developing nations, and discuss both advances and persistent barriers to the implementation of telesonography programs. Hypothesis: The use of a store-and-forward telesonography system in this setting will increase the speed and number of final diagnoses per scan received by the target clinic and will increase the continuity of care by increasing the number and speed of follow-up appointments to the target clinic.

NCT ID: NCT00590759 Completed - Clinical trials for Aortic Aneurysm, Thoracic

Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms

Start date: August 2005
Phase: N/A
Study type: Interventional

The purpose of this post-approval study is to evaluate the long-term performance of the GORE TAG® Thoracic Endoprosthesis (TAG device) in the primary treatment of descending thoracic aortic (DTA) aneurysms

NCT ID: NCT00587977 Completed - Clinical trials for Abdominal Aortic Aneurysm

Aortic Distensibility

FAMRI
Start date: November 2004
Phase: N/A
Study type: Observational

Can software be developed to automatically aid in the measurement of abdominal aortic aneurysms, and is there a way to predict future rupture or growth of abdominal aortic aneurysms.

NCT ID: NCT00583414 Completed - Clinical trials for Abdominal Aortic Aneurysm

Endovascular Exclusion of Abdominal Aortic Aneurysms in High Risk Patients

Start date: September 1998
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the role of abdominal aneurysm and iliac aneurysm exclusion using an endovascular prosthesis.

NCT ID: NCT00583050 Completed - Clinical trials for Abdominal Aortic Aneurysm

Endovascular Exclusion of TAAA/AAA Utilizing Fenestrated/Branched Stent Grafts

Start date: February 2001
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the role of fenestrated/branched stent-grafts in the exclusion of abdominal aortic and thoracoabdominal aneurysms.

NCT ID: NCT00543270 Completed - Clinical trials for Abdominal Aortic Aneurysm

Powerlink Bifurcated Stent Graft Long-Term Follow-up Study

Start date: October 2005
Phase: N/A
Study type: Interventional

Endologix Infrarenal Bifurcated Stent Graft Study

NCT ID: NCT00538967 Completed - Clinical trials for Aortic Aneurysm, Abdominal

The Effect of Doxycycline on Matrix Metalloproteinase Expression and Activity in the Abdominal Aneurysm

Start date: May 2002
Phase: Phase 2
Study type: Interventional

The matrix metalloproteinase-9 (MMP-9) is considered to play a central role in abdominal aortic aneurysm (AAA) initiation. Doxycycline has direct MMP-9 inhibiting properties in vitro, and it effectively suppresses AAA development in rodents. Observed inhibition of AAA progression, and contradictory findings in human studies evaluating the effect of doxycycline therapy on aortic wall MMP-9 suggest that the effects of doxycycline extend beyond MMP-9 inhibition, and that the effect may be dose dependent.

NCT ID: NCT00538421 Completed - Surgery Clinical Trials

Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery

ABSENT
Start date: March 2008
Phase: Phase 4
Study type: Interventional

Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.

NCT ID: NCT00522535 Completed - Clinical trials for Abdominal Aortic Aneurysms

Prospective Aneurysm Trial: High Angle Aorfix™ Bifurcated Stent Graft

PYTHAGORAS
Start date: April 2006
Phase: N/A
Study type: Interventional

Purpose of this study: The purpose of the study is to evaluate the safety and effectiveness of the Lombard Medical endovascular Aorfix™ AAA bifurcated stent graft in the treatment of abdominal aortic, aorto-iliac and common iliac aneurysms with anatomies including angled aorta, angled aneurysmal body, or both, between 0° and 90°. Study hypothesis: The primary efficacy hypothesis is the proportion of grafts remaining free from endoleak, migration, and fracture at 12 months. Efficacy: The 12 month, all cause mortality rate in the Aorfix™ group will be non-inferior to the 12 month, all cause mortality rate in the Open Control group. Safety: The rates of early serious adverse events between 0 and 30 days post-operative in the Aorfix™ groups will be non-inferior to the early serious adverse event rates between 0 and 30 days post-operative in the Open Control group.

NCT ID: NCT00513773 Completed - Clinical trials for Aortic Aneurysm, Abdominal

Inflammation and Risk Prediction in Patients With Abdominal Aortic Aneurysm

Start date: July 2008
Phase: N/A
Study type: Observational

The purpose of this study is to better understand the role of inflammation in the pathophysiology of abdominal aortic aneurysm. In this study we hope to show better ways of predicting risk in this condition by using a combination of FDG-PET with CT.