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Cannabidiol Effects on Learning and Anxiety

Anxiety and Fear Clinical Trial

Official title:
Cannabidiol Effects on Learning and Anxiety

Clinical Trial Summary

To examine the extent to which Cannabidiol (CBD) enhances fear conditioning extinction in college undergraduates who show elevated social anxiety. Undergraduates who display elevated social anxiety on standard assessments will be recruited at the University of Connecticut. All participants will be put in a standard fear conditioning paradigm where they are conditioned to fear a face that occasionally is followed by a shock to their wrist. The other face never is paired with a shock. After everybody learns this, half of the participants will receive 600 mg CBD Isolate Gel Capsules one time, and the other half will receive a placebo dose. Participants will then be presented with the faces with no shocks, and the rate and duration of extinction as measured by electrodermal response as well as subjective fear ratings via a visual analogue scale will be examined. It is hypothesized that participants that receive CBD will display enhanced extinction compared to the placebo group, as evidenced by reduced electrodermal response and reduced visual analogue fear ratings.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05283382
Study type Interventional
Source University of Connecticut
Contact Robert Astur, PhD
Phone 18609851239
Email robert.astur@uconn.edu
Status Not yet recruiting
Phase Early Phase 1
Start date February 1, 2024
Completion date February 1, 2025
View Details
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