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Platelet Reactivity And Clinical ThrombotIC Events Study — PRACTICE  

Acute Coronary Syndrome Clinical Trial

Official title:
Platelet Reactivity And Clinical ThrombotIC Events Study

Clinical Trial Summary

Platelet function testing has been considered for DAPT strategy adjustments to reduce the patient's risk of ischemia and bleeding. Although several previous RCT studies did not find any benefit in the detection of platelet function， the previous studies were mostly low-risk populations, and the P2Y12 receptor antagonists were simply clopidogrel, and the detection methods were relatively simple. Therefore, the need for platelet monitoring in high-risk ACS patients receiving new potent P2Y12 inhibitor ticagrelor, as well as the diagnostic threshold for different platelet function assays needs further study. In addition, due to the differences on the response to anti-platelet drugs between the East and the West, it is not appropriate to simply refer to the conclusion of the other party. However, as of now, there is no large sample randomized controlled study systematically focused on the applicability and status of platelet function tests in East Asian populations, especially Chinese populations.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03525145
Study type Observational [Patient Registry]
Source Shenyang Northern Hospital
Contact Yi Li, MD
Phone 86-13309886850
Email doctorliyi@126.com
Status Recruiting
Phase
Start date September 1, 2018
Completion date May 31, 2020
View Details
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