Activates Charcoal for Patients Undergoing Invasive Procedure Delayed Due to Direct Oral Anticoagulants — CACAOD  

Anticoagulants; Circulating, Hemorrhagic Disorder Clinical Trial

Official title: Activates Charcoal for Patients Undergoing Invasive Procedure Delayed Due to Direct Oral Anticoagulants

Status Not yet recruiting

Clinical Trial Summary

This is a prospective, multicentric, randomized, open labeled superiority trial

This study aims to evaluate the efficacy of oral activated charcoal for improving elimination of direct oral anticoagulants ( Rivaroxaban, Apixaban) in case of an unscheduled invasive procedure delayed to this anticoagulant treatment.

The primary outcome is the anticoagulant's half life. Plasma concentration will be measured by liquid chromatography-mass spectrometry for the main analysis (pharmacokinetic).

A total of 140 patients will randomly be assigned to the charcoal or control group, stratified according to their anticoagulant drug.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Anticoagulants; Circulating, Hemorrhagic Disorder
• Hemorrhagic Disorders

• NCT number: NCT02969746
• Study type: Interventional
• Source: University Hospital, Angers
• Contact: Thomas Moumneh, Dr
• Phone: +33241356650
• Email: thomas.moumneh@chu-angers.fr
• Status: Not yet recruiting
• Phase: Phase 4
• Start date: September 2017
• Completion date: September 2018