Nasopharyngeal Carriage of S. Pneumoniae

Status Recruiting

Clinical Trial Summary

This nasopharyngeal (NP) carriage surveillance study was requested by the European Agency for the Evaluation of Medicinal Products as a post-licensing commitment to determine whether the use of the pneumococcal conjugate vaccines (PCVs) including 7 then 13 valents (introduced in 2001 and 2010, respectively) caused a shift in the distribution of Streptococcus pneumoniae serotypes in children with acute otitis media and modified the resistance of this bacterial species to antibiotics.

Clinical Trial Description

Since September 2001, 121 pediatricians who are part of a research and teaching network (ACTIV) throughout France participated at this prospective study. From October to June of each subsequent year, children of both sexes suffering from suppurative acute otitis media (AOM) with fever and/or otalgia (in order to increase the probability of pneumococcal AOM), aged 6 to 24 months, were enrolled. And a second group of healthy children aged 6 months to 15 years were also enrolled for the main study. For ancillary study a subgroup of children were enrolled for assessment of E. coli (ESBL) resistance. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04460313
Study type	Interventional
Source	Association Clinique Thérapeutique Infantile du val de Marne
Contact	Corinne Levy, MD
Phone	0033148850404
Email	corinne.levy@activ-france.fr
Status	Recruiting
Phase	N/A
Start date	September 11, 2001
Completion date	December 1, 2024

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT03781817` - Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures	Phase 4
Recruiting	`NCT05424757` - Polyethylene Glycol Safety in Children
Recruiting	`NCT04602429` - Children's Acute Surgical Abdomen Programme
Recruiting	`NCT05378581` - Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children	N/A
Completed	`NCT04933734` - Turkish Cultural Adaptation, Validity and Reliability of the "Physical Activity-Specific Rumination Scale for Children"
Completed	`NCT03457688` - Effect of Prebiotic Fructans to Reduce Number of Febrile Infections in Children	N/A
Recruiting	`NCT05113420` - The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations
Completed	`NCT03241355` - Prebiotic Fructans on the Incidence of Acute Infectious Diseases in Children	N/A
Not yet recruiting	`NCT05484102` - Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children	N/A
Not yet recruiting	`NCT05974917` - Serious gaMes as Emerging E-health Interventions for Young People With neurologicaL or rEspiratory disoRders
Completed	`NCT06451289` - Study on Optic Nerve Sheath Diameter Measurements in Prolonged Pediatric Seizures
Completed	`NCT04057612` - Correlation Between Core Temperature and Skin Temperature in Pediatrics
Completed	`NCT04256590` - Tongue Depressor-related Tongue Swelling
Recruiting	`NCT03319927` - Reducing Pesticide Exposures in Child Care Centers	N/A
Enrolling by invitation	`NCT05513235` - Feasibility Study of a Mobile Digital Personal Health Record for Family-Centered Care Coordination for Children and Youth With Special Healthcare Needs	N/A
Completed	`NCT04615000` - SeroCovid<19: Covid-19 Seroconversion in Tertiary Pediatric Patients
Not yet recruiting	`NCT05568849` - Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery	N/A
Recruiting	`NCT06157346` - Characteristics of Intestinal Bacteria and Their Effects on Growth and Immune Function in Children at High Altitude
Recruiting	`NCT04206956` - Anxiety and Chronic Postsurgical Pain Following Ambulatory Surgery in Children
Completed	`NCT04315220` - Corestability Training in Overweight Children	N/A