SARS CoV 2 Infection Clinical Trial
— COVANOSOfficial title:
SARS-CoV-2 Infection/Covid-19 and Anosmia - Prevalence Study, Molecular Analysis and Clinical Trial
Verified date | February 2022 |
Source | University College, London |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Our study aims to determine the prevalence of anosmia in patients SARS-Cov-2/Covid-19 infection (both by symptom reporting and smell testing), the efficacy of early olfactory training for the treatment of anosmia caused by infection and the long-term impact of smell dysfunction with a one-year follow-up.
Status | Completed |
Enrollment | 63 |
Est. completion date | August 8, 2021 |
Est. primary completion date | August 8, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Confirmed (positive laboratory antigen test) or suspected COVID-19 infection - Sudden onset of smell loss - Smell loss of at least 4 weeks - Reduced smell function through psycho-physical testing (Brief Smell Identification Test score of 8 or less) Exclusion Criteria: - |
Country | Name | City | State |
---|---|---|---|
United Kingdom | James Paget and Norfolk & Norwich University Hospitals | Gorleston-on-Sea | Great Yarmouth |
United Kingdom | Barts Health NHS Foundation Trust | London | England |
United Kingdom | Guy's and St. Thomas' NHS Foundation Trust | London | England |
United Kingdom | Wrightington, Wigan and Leigh NHS Foundation Trust | Wigan | England |
Lead Sponsor | Collaborator |
---|---|
University College, London |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Brief Smell Identification Test (BSIT) | The absolute difference between the intervention and control arms in BSIT score smell improvement, measured as a change from baseline at 12-weeks. | 12-weeks | |
Secondary | Quality of Life Score | Within subject changes to scoring of questionnaire quality of life items at 12-weeks compared to baseline | 12-weeks | |
Secondary | Compliance (anecdotal) | Participant compliance to olfactory training through anecdotal reporting | 12-weeks | |
Secondary | Safety (anecdotal) | Safety of the use of Sniffin' Sticks through anecdotal reporting | 12-weeks |