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Anorexia clinical trials

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NCT ID: NCT05911334 Terminated - Anorexia Nervosa Clinical Trials

Feasibility of the ROADE Program

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Occupational therapy is uniquely poised to help address chronic Eating Disorders (EDs) because of our holistic approach to client care. The complex and serious nature of EDs spans so many areas of life and wellbeing, it requires an intervention strategy that addresses the whole person across mental, physical, social, and spiritual realms. Unfortunately, specialized care for EDs can be difficult to find - especially for those not sick enough to be admitted to an inpatient facility but who are still struggling to thrive in daily life. For example, in New Mexico there is only one inpatient treatment center for EDs and no specialized outpatient services. This leaves many people suffering from EDs without options for care because they are not yet sick enough. There is a need for novel interventions in this setting that go beyond the traditional weight and food-focused medical interventions and seek to help empower individuals, work around challenges, and live their lives to the fullest. To meet this need in our community, the study team is developing a preliminary outpatient treatment program. The ROADE (Restorative Occupational Approaches for Disordered Eating) Program is an 8-week, structured, multimodal intervention seeking to reduce psychosocial symptoms and improve self-management skills for disordered eating. The intervention strategies range from: (1) wellness activities like mindfulness meditation to improve interoception, self-acceptance, and as a self-guided coping tool (2) adaptation of health management and self-care occupations to improve daily functioning while navigating ongoing disordered eating symptoms and (3) light exercise like Yoga and lymphatic drainage exercises to reconnect in a positive way with the body, improve digestion, promote relaxation, and reduce muscle tension. The current research investigates the feasibility and acceptability of this intervention while testing preliminary effects on eating disorder symptoms.

NCT ID: NCT05073679 Terminated - Eating Disorders Clinical Trials

Oral Naltrexone In Pediatric Eating Disorders

ONPED
Start date: April 22, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo. Study participants will be patients in a partial hospitalization program or intensive outpatient program for eating disorder.

NCT ID: NCT04233450 Terminated - Anorexia Nervosa Clinical Trials

Perceptions of Their Own Body and of the Body of Their Child Among Young Mothers With Anorexia Nervosa

BodyBabe
Start date: January 26, 2020
Phase:
Study type: Observational

The BodyBabe studies aims to evaluate the perceptions that young mothers with anorexia nervosa (active or in remission) have of their own body and of the body of their child. The evaluations are carried out with self-assessment questionnaires and silhouette scales at three time points: D0 (during the stay at the maternity hospital), D15 (15 days after delivery) and M9 (9 months after delivery). The output expected from this study is to validate a questionnaire to help healthcare providers to adapt their care of women with anorexia nervosa during the pregnancy and the post-partum period.

NCT ID: NCT04185727 Terminated - Exercise Clinical Trials

Training Intervention in the Treatment of Anorexia Nervosa

STRONG_2
Start date: December 5, 2019
Phase: N/A
Study type: Interventional

The scope of the STRONG_2 project is to investigate the effect of supervised exercise as add-on to standard of care (SOC), for patients with eating disorders (EDs). The effect of supervised strength training will be measured on health parameters such as muscle strength. The study includes patients diagnosed with anorexia nervosa and in treatment at the Mental Health Center Ballerup (PCB) in the Capital Region of Denmark.

NCT ID: NCT04028635 Terminated - Anorexia Nervosa Clinical Trials

Treating the Fear of Gaining Weight in Anorexia Nervosa

Start date: February 25, 2019
Phase: N/A
Study type: Interventional

The main aim of this study is to develop a virtual reality (VR) embodiment-based exposure technique to improve the treatment of anorexia nervosa (AN). A systematic and hierarchical body exposure intervention in which the patient owns a virtual avatar is proposed. At first, the virtual body matches with the real measurements of the patient, then the experimenter will progressively increase Body Mass Index (BMI) values of the virtual body during the exposure sessions until a healthy BMI value is reached (e.g. BMI score of 20). In this study a VR embodiment-based technique that combines visuo-motor and a visuo-tactile stimulation procedures is proposed in order to increase illusory feelings of ownership over the virtual body. It is hypothesised that adding a VR-based body exposure intervention to the classical cognitive behavioral therapy (CBT) will significantly reduce symptomatology in AN patients.

NCT ID: NCT03948217 Terminated - Anorexia Nervosa Clinical Trials

The Effects of Artificial Lighting on Affective and Core Symptoms of Eating Disorder

METROPOLIS
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The primary objective of this pilot study is to explore the effect of artificial lighting on affective symptoms, and the secondary aim is to explore the effect of artificial lighting on core symptoms of eating disorders (ED). Several lines of evidence, albeit from hypothesis generation studies, suggest that artificial lighting may have a positive effect on well-being, mental health and affective symptoms in ED. The rationale of this study is to investigate the effects of artificial lighting on affective symptoms and cores symptoms of ED in inpatients undergoing weight restoration/treatment for ED. Study design: Single-blind, controlled, pilot intervention study with circadian light (CL) comparing two CL regimens effects on mood symptoms. Planned number of subjects: 16 patients with a ICD-10 diagnosis of Anorexia Nervosa, that completes exposure to at least three weeks of the two different CL regimens (L1 and L2) in any order.

NCT ID: NCT03813355 Terminated - Anorexia Nervosa Clinical Trials

Evaluation of tDCS Efficacy in Enduring Anorexia Nervosa

EVASTRAM
Start date: October 21, 2020
Phase: N/A
Study type: Interventional

Approximately 20% of anorexia nervosa cases do not respond to conventional management strategies: cognitive behavioral therapy, weight gain contract, drug treatments, etc ... - whether they are applied outpatients or during very long hospitalizations. These situations of chronic evolution are characterized by a high rate of mortality. Brain stimulation could be an alternative therapy for these patients. tDCS (transcranial direct current stimulation) is a non-invasive stimulation technique that has demonstrated beneficial effects in other psychiatric conditions such as major depression or schizophrenia. The objectives of the study will be to evaluate the efficacy of tDCS in anorexia nervosa resistant to conventional treatments on weight gain, eating behavior, psychological and nutritional behavioral scales, cognition, connectivity and brain activity.

NCT ID: NCT03172533 Terminated - Anorexia Nervosa Clinical Trials

Estrogen Replacement in Anorexia Nervosa

HOSAN
Start date: March 15, 2016
Phase: Phase 2
Study type: Interventional

The present study is a placebo-controlled randomised study on the effects of estrogen replacement upon AN-associated psychopathology, several neurocognitive domains and appetite-regulating circuits in female patients with AN. The investigators aim at assessing peripheral concentrations of neuroendocrinological components of the Hypothalamus-Pituitary-Gonadal (HPG) and Hypothalamus-Pituitary-Adrenal (HPA) axis, as well as appetite-regulating hormones in AN and to examine associations with AN-associated psychopathology and neurocognitive performances before (baseline), during and after inpatient psychotherapy of female patients receiving concomitant treatment with estrogens (vs. placebo).

NCT ID: NCT03151135 Terminated - Anorexia Nervosa Clinical Trials

Energy Turnover in Patients With Anorexia Nervosa

Start date: March 1, 2017
Phase:
Study type: Observational

Pilot study to assess energy turnover at end of inpatient treatment in 10 patients with Anorexia nervosa.

NCT ID: NCT03118921 Terminated - Anorexia Clinical Trials

Body Image Disorder in Anorexia Nervosa and Virtual Reality

REVAM
Start date: April 20, 2017
Phase: N/A
Study type: Interventional

Evaluation of the tolerance and acceptability of the virtual representation of its body image.