Interoceptive Exposure for Adolescents With Low Weight Eating Disorders

Anorexia Nervosa Clinical Trial

Official title: A Confirmatory Efficacy Study of Interoceptive Exposure for Adolescents With Low Weight Eating Disorders

Status Recruiting

Clinical Trial Summary

This project includes a parallel group randomized controlled trial comparing two psychological treatments: 1) Exposure-based Family Therapy (IE) vs. 2) Family Based Therapy (FBT) for low weight eating disorders with 12 month follow-up. Primary outcomes are expected body weight and clinical impairment. Three mechanisms of change (Autonomous Eating, Non-Judgmental Body Awareness, and Extinction Learning) will be examined in a process mediation models of change.

Clinical Trial Description

A total of 120 individuals with Anorexia Nervosa ages 12-18 will be enrolled to either 20 sessions of outpatient Exposure-based Family Therapy (IE) or Family Based Therapy (FBT). The aims of the study are to test the comparative efficacy and primary mechanisms of change after 6 months of treatment and at one year post-treatment and to explore the mediators and moderators of the primary outcomes at these endpoints. All recruitment and study procedures will take place through the Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai. Assessments will take place at 2-, 4-, 6-, 12-, and 18-months following baseline. ;

Related Conditions & MeSH terms

• Anorexia
• Anorexia Nervosa
• Feeding and Eating Disorders

• NCT number: NCT05763849
• Study type: Interventional
• Source: Icahn School of Medicine at Mount Sinai
• Contact: Thomas Hildebrandt, Psy.D.
• Phone: (212) 659-8673
• Email: tom.hildebrandt@mssm.edu
• Status: Recruiting
• Phase: N/A
• Start date: March 14, 2023
• Completion date: January 2028