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Influence of Reward and Punishment on Goal-directed and Habit Learning in Adolescent Anorexia Nervosa

Anorexia Nervosa Clinical Trial

Official title:
Influence of Reward and Punishment on Goal-directed and Habit Learning in Adolescent Anorexia Nervosa

Clinical Trial Summary

The proposed study of adolescents with anorexia nervosa (AN) will examine the association of behavioral differences in constructs of decision making, brain structure and connectivity, and eating disorder (ED) symptoms. This study tests the novel hypothesis that goal-directed and habit learning for reward and punishment is altered in AN and is uniquely associated with divergent symptoms and differences in corticostriatal connectivity and microstructural integrity. We will recruit 78 females currently ill with AN and 26 controls ages 13-17 to investigate how goal-directed and habit learning for reward and punishment correspond to 1) clinical symptoms collected via interviews, self-report assessments, and ecological momentary assessment (EMA), and 2) brain structure and connectivity in the resting state. Data collection will rely on a technology called functional magnetic resonance imaging (fMRI).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04051879
Study type Observational
Source University of California, San Diego
Contact
Status Active, not recruiting
Phase
Start date April 1, 2019
Completion date April 1, 2025
View Details
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