Ghrelin With Anorexia Nervosa

Anorexia Nervosa Clinical Trial

Official title:

Level of Ghrelin With Anorexia Nervosa (AN) Patients. Subgroup AN: With and Without Tubefeeding.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00825461
• Other study ID #: 08-3-089
• Status: Completed
• Phase: N/A
• First received: January 20, 2009
• Last updated: January 5, 2018
• Start date: March 2009
• Est. completion date: December 31, 2012

Study information

• Verified date: September 2009
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The PICOWO research group in corporation with the University of Amsterdam (Artificial Intelligence) has developed a computer simulationmodel of eating disorders (Bosse, Delfos, Jonker & Treur, 2003). In a running Phd project we want to add ghrelin to the model. The idea for this current research is to collect clinical information about the functioning and (patho)physiology of ghrelin in patients with AN, so we can extend the simulation.

Description:

Eating disorders are in need of new perspectives. A better understanding of the appetite in patients with eating disorders, especially Anorexia Nervosa, could be investigated by the levels of ghrelin in patients with and without tube feeding.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: December 31, 2012
• Est. primary completion date: December 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 12 Years to 35 Years

Eligibility

Inclusion Criteria:

• Studypopulation: Patiënts: all female, non -age coupled.

• Subgroup patients without tube feeding, with tube feeding and a healthy matched control group.

• Control group: healty volunteers of the University of Maastricht.

Exclusion Criteria:

• Patients with a history of eating disorder different than AN or a psychiatric history.

• Control group: no history of eating disorders or other psychiatric disabilities. Normal physical examination, ecg, laboratorium (blood cells, liver, kidneys)

Related Conditions & MeSH terms

• Anorexia
• Anorexia Nervosa

Locations

Country	Name	City	State
Netherlands	University Hospital Maastricht	Maastricht	Limburg

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands, 

References & Publications (2)

Bosse, T.; Delfos., M.F.; Jonker, C.M. & Treur, J. (2003). Reasoning about adaptive Dynamical Systems in the Analysis of eating Regulation Disorders. N.J. Mahwah. Proceedings of the 25th Annual Conference of the Cognitive Science Society. Lawrence Erlbaum Associates Inc.

Both, F. & Delfos, M.F. (in preparation). The role of ghrelin in eating disorders, a review.

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Concentration of ghrelin in blood.		1 morning