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Anodontia clinical trials

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NCT ID: NCT04713800 Recruiting - Clinical trials for Jaw, Edentulous, Partially

Two-unit Cantilever Implant Prostheses Made of Monolithic Zirconia or PFM

Cantilever
Start date: July 28, 2021
Phase: N/A
Study type: Interventional

The aim of is to compare the survival rate and technical outcomes of cantilever implant-supported fixed denture prosthetics (cFDPs) made either out of monolithic zirconia bonded to a titanium base in a digital workflow, or porcelain fused-to metal using a gold abutment in a conventional workflow. In addition, biological outcomes, wear patterns, PROMs and time efficiency will be recorded. The null hypothesis is: the reconstruction type does not influence the survival rate and technical outcomes of 2-unit implant-supported cFDP.

NCT ID: NCT04581304 Recruiting - Bone Loss Clinical Trials

The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.

Start date: October 15, 2020
Phase: N/A
Study type: Interventional

To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.

NCT ID: NCT04221243 Recruiting - Missing Teeth Clinical Trials

Evaluation Of Innovative 3D Printed Space Maintainer Versus Conventional One

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The primary aim of this study is to introduce a new effective and efficient 3D printed design of an intra-oral space maintainer. The secondary aim of the study is to: Evaluate the clinical performance of 3D printed space maintainer versus conventional metal band and loop over a period of 6 months regarding their functional , biological aspects and patient satisfaction.

NCT ID: NCT04153851 Recruiting - Missing Teeth Clinical Trials

Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Study the effect of neurectomy of nasopalatine nerve on the sensation of anterior palate in patients undergoing rehabilitation of anterior maxillary ridge with dental implant

NCT ID: NCT04041518 Recruiting - Missing Tooth Clinical Trials

Autotransplantation of Teeth With Intraoperative Extra-corporal Apicoectomy

ZahnTx
Start date: January 29, 2019
Phase: N/A
Study type: Interventional

Clinical trial to evaluate the success rate of autotransplantation of teeth with advanced or completed root growth with intraoperative extracorporeal root tip resection in 20 patients.

NCT ID: NCT03445026 Recruiting - Hypodontia Clinical Trials

Frequency of Hypodontia After Chemotherapy in Childhood Cancer Survivors Study

Start date: January 1, 2018
Phase: N/A
Study type: Observational

This study aims to provide information on the frequency of hypodontia in children cancer survivors receiving chemotherapy before 4 years of age.Patients who met the eligibility criteria will be given a structured questionnaire to fill followed by a radiographic examination (dental panorama) for confirmation and standardization of the results.

NCT ID: NCT02898311 Recruiting - Clinical trials for Dental Implant Failed

One-Tooth One-Time (1T1T) A Straightforward Approach to Replace Missing Teeth in the Posterior Region: a Case Series

1T1T
Start date: July 2016
Phase: N/A
Study type: Interventional

This study evaluates the success rate, as the biological and prosthesis complications, of posterior single-unit implants immediately loaded with a chair side Computer-Aided Design and Manufacturing (CAD-CAM) composite crown, after a follow-up period of 6 months,1,2,3,4 and 5 years. Complementary ex vivo analyses will be performed to evaluate the wear of restorations. The time and cost benefit of the presented digital workflow, as patient centered outcomes will also be evaluated.

NCT ID: NCT00026026 Recruiting - Anodontia Clinical Trials

Linkage and Identification of (a) Candidate Gene(s) for Tooth Disorders

Start date: n/a
Phase: N/A
Study type: Observational

The congenital absence of teeth, commonly referred to as hypodontia or tooth agenesis, is a common developmental anomaly of human dentition that affects approximately 20% of the population. Although new genetic and molecular approaches in humans and mice have increased our understanding of the molecules that control tooth patterning (number, position, shape and size), the precise nature of the genes involved in hypodontia in humans is poorly understood. Hence, understanding the molecular basis for missing teeth is an issue of paramount importance that is both timely and significant to the practice of dentistry. So far, only two genes have been associated with non-syndromic familial tooth agenesis: MSX1 and PAX9. Substitution mutations in the homeodomain region of MSX1 were linked to premolar agenesis while an insertion mutation in the paired box domain of PAX9 was shown to be responsible for molar oligodontia. The long-term goals of this research are to elucidate the molecular pathology of human tooth agenesis, in particular, to evaluate whether genes other than MSX1 and PAX9 (locus heterogeneity) are involved. Alternatively, as in the case of MSX1, it will be interesting to know whether allelic variations, different mutations in these genes, are associated with tooth agenesis. We propose to study a potentially large kindred that report the developmental absence of several posterior teeth. The fundamental hypothesis to be tested states that the gene responsible for the congenital absence of molar teeth in this kindred is a critical element in the genesis of molars. The specific goals are to perform linkage analysis followed by direct sequencing of PCR products to identify the gene and to characterize the nature of the underlying defect. Identifying the underlying gene defect in this family affected by tooth agenesis will add new knowledge to our understanding of the pathogenesis of this defect and will provide the basis for future studies.