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Ankle Sprain clinical trials

View clinical trials related to Ankle Sprain.

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NCT ID: NCT00927641 Completed - Ankle Sprain Clinical Trials

HKT-500 in the Treatment of Adult Patients With Ankle Sprain

Start date: July 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.

NCT ID: NCT00869180 Completed - Acute Pain Clinical Trials

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain

SUPPORT 2
Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate ankle sprains when applied to the painful area.

NCT ID: NCT00847769 Completed - Ankle Sprain Clinical Trials

Ankle Sprains and Corticospinal Excitability

ACE
Start date: December 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine changes in the brain associated with improvement in ankle range of motion following ankle manual therapy procedures in individuals with post-acute ankle sprains

NCT ID: NCT00797368 Completed - Ankle Sprain Clinical Trials

Manual Therapy and Exercise Versus Home Exercises in the Management of Patients Status Post Ankle Sprain

Start date: November 2008
Phase: N/A
Study type: Interventional

A recent study has demonstrated that a physical therapist directed exercise program did not result in greater reductions in disability and pain when compared to a home exercise program. However, no manual therapy procedures were incorporated into the physical therapy treatment program despite recent evidence suggesting that thrust and non-thrust manual therapy techniques may be beneficial in reducing disability, pain and improving gait. Therefore, the purpose of this study is to compare the effectiveness of a physical therapy management approach consisting of manual therapy and exercise to a home program of exercise only. The investigators hypothesize that the group receiving manual therapy and exercise will have better outcomes.

NCT ID: NCT00732017 Completed - Ankle Sprain Clinical Trials

Effects Of High Voltage Pulsed Current On Post-Traumatic Injuries

Start date: February 2004
Phase: N/A
Study type: Interventional

The investigators hypothesis is that HVPC with negative polarity diminishes local post-traumatic edema in ankle sprains. Therefore, the objective of this study was to analyze the effect of HVPC on edema secondary to ankle sprains in humans.

NCT ID: NCT00680784 Completed - Ankle Sprain Clinical Trials

HKT-500 in Adult Patients With Ankle Sprain

Start date: April 2008
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.

NCT ID: NCT00640705 Terminated - Ankle Sprain Clinical Trials

Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain

Start date: January 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area. In this study, the location being studied will be either the left or right ankle. The secondary purpose of this study is to assess the safety and tolerability of a diclofenac patch on the skin.

NCT ID: NCT00601471 Completed - Ankle Injuries Clinical Trials

Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability

Start date: April 2007
Phase: N/A
Study type: Interventional

The overall aim of this project is to determine the effect of a tibiofibular joint manipulation on the neuromuscular response of the fibularis longus and soleus muscles in individuals with chronic ankle instability. Another aim of this study is to determine the long term effects of a tibiofibular joint manipulation on range of motion and self-reported function. We hypothesize that a manipulation applied at the distal tibiofibular joint will result in greater muscle activation, improved functional dorsiflexion ROM, and increases in FAAM scores compared to a tibiofibular joint manipulation applied at the proximal joint. We further hypothesize that both distal and proximal tibiofibular joint manipulations will result in greater muscle activation, improved functional dorsiflexion ROM, and increases in FAAM scores than no treatment at all.

NCT ID: NCT00573768 Completed - Ankle Sprain Clinical Trials

Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel in Patients With Acute Ankle Sprain

Start date: November 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy of diclofenac diethylamine 2.32% gel in the treatment of acute ankle sprain.

NCT ID: NCT00446797 Completed - Ankle Sprain Clinical Trials

Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain

Start date: May 2007
Phase: Phase 4
Study type: Interventional

To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.