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Ankle Injuries clinical trials

View clinical trials related to Ankle Injuries.

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NCT ID: NCT00955513 Completed - Clinical trials for Grade I/II Ankle Sprain

Evaluate the Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel Applied Twice or Three Times Daily in Patients With Acute Ankle Sprain

Start date: July 2009
Phase: Phase 3
Study type: Interventional

The main purpose of this trial is to compare the efficacy and safety of diclofenac diethylamine 2.32% gel applied twice (b.i.d) or three times a day (t.i.d.) with placebo in the treatment of acute ankle sprains (distortions).

NCT ID: NCT00954330 Completed - Ankle Injury Clinical Trials

Surgical Versus Functional Treatment for Acute Ruptures of the Lateral Ligament Complex of the Ankle in Young Males - A Randomized Controlled Trial With a Mean of 14 Years Follow-up

Start date: February 1991
Phase: N/A
Study type: Interventional

The aim of this prospective randomized controlled trial was to compare the effectiveness of surgical and conservative treatment in acute lateral ligament injury of ankle. The more detailed aims were to assess the function, physical activity level, re-injuries, objective stability and radiographic changes seen by magnetic resonance imaging in patients randomized to surgery or to functional treatment after a mean of 14 years follow-up.

NCT ID: NCT00927641 Completed - Ankle Sprain Clinical Trials

HKT-500 in the Treatment of Adult Patients With Ankle Sprain

Start date: July 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.

NCT ID: NCT00906672 Completed - Ankle Injuries Clinical Trials

Medico Economic Evaluation of Dermal Substitute Integra® for Coverage of Inferior Limb Traumatic Skin Loss

INTEGRA®
Start date: June 2009
Phase: Phase 3
Study type: Interventional

Comparison of 2 techniques of surgery on patients with inferior limb traumatic wounds: the innovative technique Integra® and the technique of reference: the flap surgery.

NCT ID: NCT00884988 Suspended - Fracture Clinical Trials

Lymphomyosot for Ankle Edema Following Fracture

Start date: February 2010
Phase: Phase 2
Study type: Interventional

Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks. The delay in surgical treatment can increase the risk for local skin and bone complications, as well as for deep venous thrombosis. Lymphomyosot® is a non-prescription, homeopathic complex drug which has been used for more than 70 years throughout Europe and the U.S., primarily for tissue edema and swelling. This is a randomized, placebo-controlled, double blind pilot study evaluating the effectiveness of homeopathic combination drug Lymphomyosot® compared to placebo treatment. The study will take place at the Shaare Zedek Medical Center in Jerusalem, Israel. Adult patients (age 18 years and older) admitted to the orthopedic department with acute ankle fractures which require ORIF repair will be assessed for inclusion in this study. The primary outcome measure to be evaluated is the fracture-ORIF waiting period. Other measures to be evaluated are: peri-malleolar circumference; pain (as measured by NRS and analgesic use); duration of hospital stay; and complications such as poor wound healing, blisters, and the development of deep vein thrombosis.

NCT ID: NCT00869180 Completed - Acute Pain Clinical Trials

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain

SUPPORT 2
Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate ankle sprains when applied to the painful area.

NCT ID: NCT00847769 Completed - Ankle Sprain Clinical Trials

Ankle Sprains and Corticospinal Excitability

ACE
Start date: December 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine changes in the brain associated with improvement in ankle range of motion following ankle manual therapy procedures in individuals with post-acute ankle sprains

NCT ID: NCT00797368 Completed - Ankle Sprain Clinical Trials

Manual Therapy and Exercise Versus Home Exercises in the Management of Patients Status Post Ankle Sprain

Start date: November 2008
Phase: N/A
Study type: Interventional

A recent study has demonstrated that a physical therapist directed exercise program did not result in greater reductions in disability and pain when compared to a home exercise program. However, no manual therapy procedures were incorporated into the physical therapy treatment program despite recent evidence suggesting that thrust and non-thrust manual therapy techniques may be beneficial in reducing disability, pain and improving gait. Therefore, the purpose of this study is to compare the effectiveness of a physical therapy management approach consisting of manual therapy and exercise to a home program of exercise only. The investigators hypothesize that the group receiving manual therapy and exercise will have better outcomes.

NCT ID: NCT00785876 Completed - Ankle Injury Clinical Trials

Implementation of the Low Risk Ankle Rule

Start date: November 2008
Phase: N/A
Study type: Interventional

Ankle injuries are a very common injury in children. Each year approximately 35000 kids present to Ontario emergency departments (ED) with this problem. Right now, about 90% of these children get x-rays of the injured ankle, even though only 12% of these x-rays show a break in the bone. Some excellent research has created some rules that doctors can use to help them decide which children really need x-rays. Unfortunately, even though these rules have been proven to safely reduce x-rays by as much as two-thirds, most doctors are not using these rules. Therefore, this study will be the first to put the best paediatric ankle x-ray rule, the Low Rick Ankle Rule, into physician practice in EDs. Our main goal is to determine how much we can reduce ankle x-ray rates in EDs that use this rule regularly versus those that do not. If we show that doctors can safely use this rule regularly and the number of ankle x-rays will be significantly less, this will lessen unnecessary potentially harmful radiation exposure in children, these children will spend less time in an ED, and the health care system will save money.

NCT ID: NCT00761865 Terminated - Clinical trials for Lateral Ankle Sprain

Lateral Ankle Sprain Study

Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the short term treatment outcome measures of the standard of care air cell stirrup brace to that of a high tide fracture boot in patients with lateral ankle sprains.