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Ankle Injuries clinical trials

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NCT ID: NCT01874626 Completed - Acute Ankle Sprain Clinical Trials

Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain

Start date: June 2013
Phase: Phase 3
Study type: Interventional

This is a randomized, multi-center, double-blind, placebo-controlled, multi-dose, parallel-group study. Approximately 300 subjects (150 per group) 16 years of age and older with a current (within 24 hours from Visit 1) Grade I or II ankle sprain, and who meet all eligibility criteria, will be randomized into the study and will receive either the active treatment (SST-0225 ibuprofen cream), or matching placebo. Subjects will apply an amount equivalent to a 4 inch line of investigational product to the affected ankle approximately every 4-6 hours. At Visit 1 two doses will be applied at the site. All subsequent doses of the investigational product will be applied every 4 to 6 hours with a total of 4 doses in a 24 hour period. Duration of treatment with the investigational product is 7 days.

NCT ID: NCT01853462 Completed - Ankle Sprains Clinical Trials

Effects of Two Supervised Training Programs for the Rehabilitation of Ankle Sprains

Start date: December 2014
Phase: N/A
Study type: Interventional

The purpose of this study was to determine the effects of supervised balance and proprioceptive neuromuscular facilitation (PNF) training for the rehabilitation of ankle sprains

NCT ID: NCT01779804 Completed - Ankle Injuries Clinical Trials

Triage-Based Application of OFAR on the Number of Radiographs Ordered

OFAR
Start date: January 2013
Phase: N/A
Study type: Observational

Foot and ankle injuries account for nearly two million visits to Emergency Departments (EDs) in the United States and Canada each year. Of these injured patients, only 15% are diagnosed with actual fractures of the ankle. Due to such a small percentage, the "Ottawa Ankle and Foot Rules" (OFAR) were developed, which are a set of clinical decision-making guidelines that have been shown to be effective in diagnosing ankle and foot fractures. These rules are internationally accepted by the medical community, but are inconsistently applied. At Lehigh Valley Health Network (LVHN), the ED triage nurses are routinely trained in how to use the Ottawa Ankle and Foot Rules, but the rules are not always applied which may result in unnecessary X-rays. These guidelines are current network "standard of care" (usual, established care) that allow nurses to decide treatment for foot and ankle injury patients; in other words, whether to send these patients for an X-ray or not. The research staff is conducting this study in order to find out if using these nurse-directed guidelines--on a regular and consistent basis--can decrease the number of X-rays ordered, decrease patient waiting times/length of stay (LOS) and increase patient satisfaction with their care in the ED. STUDY PURPOSE: The two main goals of this study are to find out if use of the Ottawa Ankle and Foot Rules by triage nurses can decrease the amount of X-rays ordered in the ED, as well as LOS. Secondary study goals are to: 1) see how many X-rays are ordered by physicians and physicians' assistants after patients are evaluated by the Ottawa Ankle and Foot Rules as not having had a fracture; and 2) evaluate patient and provider satisfaction with the care provided both when the Ottawa Foot and Ankle Rules are used and when they are not.

NCT ID: NCT01606501 Completed - Clinical trials for Major Bone Articular Surface Loss

Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol

OUTLET
Start date: May 2012
Phase:
Study type: Observational

The primary aim this prospective longitudinal observational outcomes study is to compare 18 month functional outcomes and health related quality of life (HRQoL) of patients undergoing salvage versus amputation following severe distal tibia, ankle and/or foot fractures with major soft tissue, bone and/or ankle articular surface loss. Functional outcomes and HRQoL will be measured using well established self reported measures, including the Veterans Rand Health Survey (VR-12) and the Short Musculoskeletal Functional Assessment (SMFA). Hypothesis 1: As a group, salvage patients with severe distal tibia, ankle and/or foot injuries with major soft tissue, bone and/or ankle articular surface loss will have similar functional outcomes and HRQoL had they undergone a transtibial amputation (within 6 weeks of injury). Hypothesis 2: The subgroup of salvage patients who have either (1) a soft tissue injury that requires tissue transfer; (2) articular damage requiring arthrodesis of the ankle joint; or (3) bone loss at the distal tibia or ankle will have better functional outcomes and HRQoL had they undergone a transtibial amputation (within 6 weeks of injury).

NCT ID: NCT01586390 Completed - Ankle Injuries Clinical Trials

Functional Treatment for Acute Ankle Sprains: Softcast Wrap Versus MOKcast

Start date: June 2009
Phase: Phase 2
Study type: Interventional

In this study we compare two treatment options for ankle sprains. 100 patients were randomised between a flexible cast treatment and a removable and adjustable brace made out of the same materials. Follow-up was 4 months. Primary outcome were functional scores. Secondary outcome measures were patient satisfaction scores with treatment as well as treatment result.

NCT ID: NCT01563289 Completed - Pain Clinical Trials

Efficacy and Safety of Ibuprofen in Patients With Ankle Injuries

Start date: February 2012
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate the efficacy and safety of Ibuprofen in patients with ankle injuries.

NCT ID: NCT01562717 Completed - Pain Clinical Trials

Efficacy and Safety of Ibuprofen in Patients With Ankle Injuries

Start date: February 2012
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate the efficacy and safety of Ibuprofen in patients with ankle injuries.

NCT ID: NCT01518335 Completed - Sprain of Ankle Clinical Trials

Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department

PRP
Start date: June 2009
Phase: N/A
Study type: Interventional

This research study hopes to determine whether or not platelet rich plasma therapy improves healing time of moderate to severe ankle sprain in comparison to standard of care therapy.

NCT ID: NCT01499966 Completed - Ankle Injuries Clinical Trials

Comparison of Plaster of Paris Against Tubigrip for the Treatment of Lateral Ankle Sprains

POPTuLAS
Start date: January 2011
Phase: N/A
Study type: Interventional

Until now very few studies have been done to compare the efficacy of tubigrips or plaster of paris in the treatment of lateral ankle sprains, the investigators aim to compare the tubigrip against plaster of paris in the treatment of lateral ankle sprains.

NCT ID: NCT01449760 Completed - Ankle Sprain Clinical Trials

Ankle Sprain Rehabilitation With the Wii Balance Board

Start date: March 2010
Phase: N/A
Study type: Interventional

Physical activity and in particular sport is beneficial to health. Nevertheless, some of these activities may create a risk of injury. Ankle sprain is the most common sport related injury. Sports that are causing the highest number of ankle sprains are: football (30%), handball-basketball-volleyball-rugby (24%), gymnastics sports (6%), skiing (6%), cycling (6%), athletics (4%) and contact sports (4%). A recent study in the Netherlands identified a total of 1.3 million sports injuries. 47% of these patients required medical care. The total costs (direct and indirect) were assessed 84.240.000 EUR per year. Prospective studies demonstrated that athletes with a ankle sprain have a twofold risk of re-injury during the first year after the trauma, and in half of patients with an ankle sprain recurrence this could lead to instability or chronic pain of the ankle. The Wii Balance Board ® is a tool that is increasingly used in the field of health. In some hospitals, therapists are beginning to use it for the rehabilitation of patients after surgery, fractures or strokes. Patients are asked to complete their physical therapy session by practicing "sports" via video games such as skiing, bowling or hula hoop. Currently, there are no randomized controlled studies that publish on the effectiveness of this tool. Recently, a study investigated the efficacy of the Wii Balance Board ® to improve balance, strength, joint mobility and level of physical activity. After 10 weeks of training, people an increased strength and balance was found. However, these results still require statistical confirmation. Thus this objectives of this study are - To assess the efficacy of exercise training with the Wii Balance Board ® Platform - To evaluate the effectiveness of physical therapy (based on current guidelines) - To compare these two types of care (conventional physiotherapy versus Wii) to a control group (non-treatment).