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Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma

Angioimmunoblastic T-cell Lymphoma Clinical Trial

Official title:
Azacytidine Combined With Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma: a Multicenter Single Arm Phase II Study

Clinical Trial Summary

This is a multicenter prospective single arm phase II study. The purpose of this study is to evaluate the safety and efficiency of azacytidine combined with chidamide in the treatment of relapsed/refractory angioimmunoblastic T-cell lymphoma.

Clinical Trial Description

Azacytidine was given subcutaneously at a dose of 75 mg/m2 on days 1-7. Chidamide was an oral tablet which was administered 20mg twice weekly. This regimen was repeated every 28 days. Treatment was given until disease progression, unacceptable toxicity, or patient/investigator discretion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05179213
Study type Interventional
Source Peking Union Medical College Hospital
Contact Chong Wei, Dr
Phone +86 13521760705
Email QH5035@163.com
Status Not yet recruiting
Phase Phase 2
Start date January 1, 2022
Completion date May 1, 2024
View Details
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