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Angina, Stable clinical trials

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NCT ID: NCT03815032 Completed - Clinical trials for Coronary Artery Disease

Assessing the Accuracy of the OptoWire DeuxTM in a Wire to Wire Comparison

ACCURACY
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The goal of the ACCURACY study is to assess the differences, if any, in FFR measurements made by the OptoWire Deux FFR guidewire by comparison of simultaneous data of two different OptoWire DeuxTM guidewires (group 1). In addition, the investigators will compare (group 2) the FFR measurements obtained from an OptoWire Deux FFR guidewire and compare it to the FFR measurement by a VERRATA-TM guidewire to assess coronary stenosis in the routine clinical practice.

NCT ID: NCT03794713 Not yet recruiting - Clinical trials for Medication Adherence

A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The present study aims to enhance the adherence of beta-blockers by Patient Support Tool through a smart phone application and a wristband, subsequently reduce the risk of angina attacks in patients with stable angina pectoris.

NCT ID: NCT03789552 Recruiting - Clinical trials for Chronic Stable Angina Pectoris

Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina

Start date: August 1, 2019
Phase: Phase 3
Study type: Interventional

This is a multi-center, double-blind, randomized, placebo-controlled, parallel-group phase 3 clinical study to confirm the safety and efficacy of T89 in patients with stable angina pectoris, with an extended open-label period to evaluate the long-term safety of T89. This study includes three main periods: the first study period is a 3-week single-blind qualifying run-in period to screen eligible stable angina patients by exercise tolerance test (ETT). The second study period is a 8-week double-blind treatment period to evaluate the efficacy and safety of T89 in patients with stable angina by ETT. And, the last study period is a 44-week open-label period to observe long-term use safety of T89.

NCT ID: NCT03783351 Recruiting - Clinical trials for Acute Coronary Syndrome

Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)

Start date: May 27, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to assess the efficacy and safety of the CYP2C19 genotype guided antiplatelet treatment strategy, using clopidogrel in non-carriers of a CYP2C19*2 or *3 allele and ticagrelor in carriers of a CYP2C19*2 or *3 allele in patients treated with new generation drug eluting stents.

NCT ID: NCT03781492 Recruiting - Clinical trials for Coronary Artery Disease

Stable Angina Management and Treatment

PRESAGE
Start date: January 1, 2006
Phase:
Study type: Observational [Patient Registry]

The Prospective REgistry of Stable Angina manaGEment and Treatment (PRESAGE) is an observational study on an all-comer stable angina population hospitalised in a highly specialized cardiovascular centre with cardiac surgery facilities. The aim of the study is to assess the clinical characteristics, treatment modalities, early and long-term outcomes in this population.

NCT ID: NCT03771053 Recruiting - Clinical trials for Coronary Heart Disease

The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

In this study, simvastatin combined with Ezeimebum was used to enhance lipid reduction, and IVUS was used to evaluate the volume and composition of coronary plaque before and after treatment. The aim is to evaluate the overall intervention effect of Ezeimebum on stable angina pectoris with diabetes mellitus on the basis of statins.

NCT ID: NCT03759067 Completed - Angina, Stable Clinical Trials

Method of Clopidogrel Pre-treatment Undergoing Conventional Coronary Angiogram in Angina Patients

MECCA
Start date: October 18, 2010
Phase: N/A
Study type: Interventional

The study included 511 patients who underwent PCI because of angina during 2010-2011 at three Korean hospitals. Clopidogrel-naïve patients received either a loading dose (LD; 600 mg at 2-24 h before the procedure) or routine maintenance therapy (75 mg/day for ≥5 days) plus either a 300-mg reload (RL) or only the maintenance dose (MD).

NCT ID: NCT03755700 Recruiting - Clinical trials for Coronary Artery Disease

Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

In a double-blinded randomized clinical trial, all patients undergoing coronary artery catheterization who will met our criteria, will be enrolled into three groups to receive either, vitamin e, n-acetylcysteine, or placebo. The aim of study will be to compare the superiority of vitamin e over n-acetylcysteine for the prevention of contrast-induced acute kidney injury (CIAKI).

NCT ID: NCT03742050 Completed - Stable Angina Clinical Trials

A Placebo-controlled Trial of Percutaneous Coronary Intervention for the Relief of Stable Angina

ORBITA-2
Start date: November 12, 2018
Phase: N/A
Study type: Interventional

ORBITA-2 is a double blinded randomised placebo-controlled trial comparing the effects of coronary angioplasty versus placebo procedure on symptoms of stable angina without background anti-anginal therapy. Follow-up will be at 12 weeks.

NCT ID: NCT03718559 Completed - Clinical trials for Coronary Artery Disease

Edoxaban Versus Edoxaban With antiPlatelet Agent In Patients With Atrial Fibrillation and Chronic Stable Coronary Artery Disease

EPIC-CAD
Start date: May 14, 2019
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy and safety of Edoxaban with the combination of edoxaban and antiplatelet in patients with stable CAD (coronary artery stenosis ≥50% on medical treatment or revascularized stable CAD [≥ 12 months for acute coronary syndrome and ≥ 6 months after stable CAD]) and high-risk atrial fibrillation (CHA2DS2-VASc score ≥2).