Angina Pectoris Clinical Trial
Official title:
Intraprocedural Determination of Myocardial Vitality Using Speckle Tracking Echocardiography Compared to Two-time MRI Diagnostics
The investigators will compare myocard vitality diagnostics using 2D-Strain echography and MRI.
Each patient with typical angina pectoris symptoms will get echocardiographic examination
during the inclusion phase. If motion disorder of regional left ventricular myocardial wall
is detected, patient will get coronary angiography (not study related, caused of typical
angina pectoris symptoms and high probability of CHD). If coronary stenosis related to
motion disorder is available, patient will be randomized in two groups during coronary
angiography.
- First Group: Patient will get echocardiographic examination during coronary
angiography. 2D-Strain Analysis will be performed based on data of this
echocardiographic examination. Only when vitality in the contraction impaired segments
will be established based on 2D-Strain Analysis, PCI (Percutaneous Coronary
Intervention) will be performed.
- Second Group: Coronary angiography by patient will be canceled. Patients will get
viability assessment using MRI(Magnetic resonance imaging) within the next 7 days. When
vitality will be established with MRI, patient will get PCI (Percutaneous Coronary
Intervention).
In addition, as part of a feasibility analysis, the possibility of a consolidation of data
of coronary angiography with the ultrasound images will be researched by first group of
patients. The aim is to simplify the visualization of the intraprocedural vitality
detection. For this purpose, a position sensor based on electromagnetic fields (EMT) will be
used during coronary angiography.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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