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The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage

Aneurysmal Subarachnoid Hemorrhage Clinical Trial

Official title:
The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage

Clinical Trial Summary

Delayed ischemia caused by cerebral vasospasm remains a common cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage. A great deal of drugs has been tested in the last years. Phase II randomized clinical trials have demonstrated that statin decreases the incidence of symptomatic cerebral vasospasm after spontaneous subarachnoid hemorrhage. Clinical, double blind, randomized controlled trials with placebo. Discussion: Even though some articles have shown that statins provide better prognosis, some issues remain in debate, e.g., treatment duration and the choice of the statin.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01346748
Study type Interventional
Source University of Sao Paulo General Hospital
Contact Flavio Romero
Phone 11-34594416
Email frromero@ig.com.br
Status Recruiting
Phase Phase 4
Start date April 2011
Completion date February 2013
View Details
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