Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

Anesthesia Clinical Trial

— EDAMTBB  

Official title:

Exploration on the Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06454513
• Other study ID #: SichuanPPHGZ03
• Status: Completed
• Start date: June 1, 2020
• Est. completion date: June 1, 2024

Study information

• Verified date: June 2024
• Source: Sichuan Provincial People's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method, operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status.

Description:

General anesthesia and local anesthesia are the primary anesthesia methods for interventional respiratory endoscopy. While general anesthesia offers greater comfort, it carries anesthesia-related risks. Local anesthesia, on the other hand, provides a relatively low surgical risk and cost-effectiveness. However, there is limited research on whether its diagnostic value is inferior to that of general anesthesia.This study investigates the efficacy of the two anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method(forcep/cryobiopsy), operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status(pneumothorax、hemorrhage).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 800
• Est. completion date: June 1, 2024
• Est. primary completion date: June 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Completed Transbronchial Biopsy;the platelets count and PT, APTT tests were normal, normal ECG, Anesthesiologist evaluation was needed in General anesthesia group.

Exclusion Criteria:

• patients with contraindication of bronchoscopy (such as respiratory failure and acute cardio-cerebrovascular events), and women who were pregnant.

Related Conditions & MeSH terms

• Anesthesia
• Biopsy
• Respiration Disorders
• Respiratory Diseases
• Respiratory Tract Diseases

Intervention

Procedure:
• general anesthesia
Different anesthesia methods

Locations

Country	Name	City	State
China	Sichuan Provincial People's Hospital	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
Sichuan Provincial People's Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Diagnostic efficacy	The diagnostic positivity rate(%) of transbronchial biopsy under different anesthesia methods between two groups	baseline
Secondary	Clinical information	age(year), gender(male/female), primary diagnosis(lung cancer/pneumonia or other)	baseline
Secondary	lesion location (left/right/other)	Clinical information	baseline
Secondary	lesion size (mm)	Clinical information	baseline
Secondary	Postoperative complications (hemorrhage or pneumothorax)	Clinical information	baseline
Secondary	Operation time	Clinical information	intraoperative