Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation

Status Recruiting

Clinical Trial Summary

Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements to guide post transplant treatment regiments. These procedures are done under general anesthesia which promotes lung tissue collapse (atelectasis). What is not known is the effect of atelectasis on intracardiac pressures which are a critical area of monitoring post-transplant patients for rejection.

Clinical Trial Description

Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements. These procedures are done under general anesthesia which promotes lung tissue collapse (atelectasis). Atalectaisis is known to alter intra-thoracic pressures and cardiac loading conditions. What is not known is the effect of atelectasis on intracardiac pressures which are a critical area of monitoring post-transplant patients for rejection. Therefore, the aim of this study is to identify if atelectasis impacts the pressure measurements obtained during cardiac catheterization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06140810
Study type	Observational
Source	Baylor College of Medicine
Contact	Adam Adler, MD
Phone	8328245800
Email	adam.adler@bcm.edu
Status	Recruiting
Phase
Start date	November 20, 2023
Completion date	November 1, 2024

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