Prediction of Hypotension During Induction of General Anesthesia

Anesthesia Clinical Trial

Official title:

Assessment of Ultrasonographic Carotid Artery Corrected Flow Time and Internal Jugular Vein Collapsibility Index in Prediction of Hypotension During Induction of General Anesthesia

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT06078228
• Other study ID #: FMASU MD205/2023
• Status: Enrolling by invitation
• Start date: September 24, 2023
• Est. completion date: August 26, 2024

Study information

• Verified date: September 2023
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Description:

• Type of Study: Observational Prospective Cohort Design.

• Study Setting and ethical consideration: The approval of the Scientific Research Ethics Committee of the Faculty of Medicine, Ain Shams University will be obtained before starting work on the study. This study will be conducted in operating theatres of Ain Shams University Hospitals. Informed written consents to participate will be obtained from the patients.

• Study Period: One year (October 2023-October 2024)

• Study Population: Adult patient undergoing elective surgeries.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 70
• Est. completion date: August 26, 2024
• Est. primary completion date: June 24, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 1- Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.

2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.

Exclusion Criteria:

• Patients with

1. Renal diseases.

2. Hepatic diseases.

3. ASA scores of 3-4.

4. The presence of a left ventricular ejection fraction less than 50%.

5. Age under 18 years old.

6. Patient refusal.

7. Coronary heart disease.

8. Cardiac disease including cardiomyopathy and mild to severe valve disease.

9. Pulmonary hypertension.

10. Peripheral arterial disease.

11. Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.

12. Any previous neck surgery or trauma.

Related Conditions & MeSH terms

• Anesthesia
• Hypotension

Intervention

Drug:
• Propfol - Fentanyl- Atracurium
investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia.

Locations

Country	Name	City	State
Egypt	Ain Shams University	Cairo	Abbassia

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the predictive value of the carotid Ftc for prediction of hypotension.	to investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia	one year