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The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty

Anesthesia Clinical Trial

Official title:
The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty

Clinical Trial Summary

The current study investigates the effect of hypotensive anesthesia on patient hemoglobin levels during primary total knee arthroplasty. Considering that because of the tourniquet there is no blood loss during the first 60 minutes of the procedure changes in hemoglobin during the first 60 minutes should be primarily related to decrease in blood pressure and secondary to fluid loading during hypotensive anesthesia.

Clinical Trial Description

The specific aim of this prospective study is to collect serial hemoglobin levels intraoperatively during hypotensive anesthesia to evaluate if intraoperative intravenous fluid substitution will change hemoglobin levels during the time the tourniquet is inflated (no blood loss). The combination of vasodilation during hypotensive anesthesia and fluid substitution will result in decrease of hemoglobin levels during the tourniquet time. Tubes of 5cc to measure hemoglobin and hematocrit levels preoperatively, prior to inflation of the tourniquet, 15 minutes, 30 minutes, 45 minutes and 60 minutes after tourniquet inflation and in PACU as well as POD 1. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05340751
Study type Observational
Source Hospital for Special Surgery, New York
Contact
Status Completed
Phase
Start date January 1, 2014
Completion date September 1, 2014
View Details
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