Ilioinguinal/Iliohypogastric Block for Inguinal Hernia Repair

Anesthesia Clinical Trial

Official title:

Postoperative Recovery Time in Inguinal Hernia Repair Under Ilioinguinal, Iliohypogastric Nerve Block and Sedation Versus General Anesthesia: a Propensity Score Matched-cohort Retrospective Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05335837
• Other study ID #: 119564
• Status: Not yet recruiting
• Start date: May 1, 2022
• Est. completion date: July 1, 2022

Study information

• Verified date: April 2022
• Source: Lawson Health Research Institute
• Contact: Cheng Lin
• Phone: 5196858600
• Email: cheng.lin[@]lhsc.on.ca
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness. Additionally, the recent COVID19 pandemic has heightened the precaution to avoid aerosol generating procedures (AGP) if possible. General anesthesia requires airway manipulation, thus necessitate performing an AGP. Recently, we began using peripheral nerve block and sedation as primary anesthetic technique for inguinal hernia repairs. While surgeon administered local anesthetic, also known as local infiltration, has been done for inguinal hernia repair, using specific nerve blocks and sedation has not been compared with general anesthesia. We believe the advantage of this novel technique can improve postoperative recovery. This retrospective study will compare the total hospital length of stay of those receiving nerve blocks and sedation as primary anesthetic techniques versus those with general anesthesia.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 350
• Est. completion date: July 1, 2022
• Est. primary completion date: June 1, 2022
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years or older

• American Society of Anesthesiologists (ASA) Physical Status I to III

• Body Mass Index (BMI) less than 45

• Single hernia repair, elective, ambulatory surgery

Exclusion Criteria:

• Opioid dependence (30 mg oral morphine equivalents daily or more)

• History of malignant hyperthermia

• Pregnancy

Related Conditions & MeSH terms

• Anesthesia
• Hernia, Inguinal

Intervention

Procedure:
• Regional Anesthesia and Sedation
Preoperative ilioinguinal/iliohypogastric nerve block and moderate to deep intraoperative sedation.

Locations

Country	Name	City	State
Canada	Cheng Lin	London	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
Lawson Health Research Institute

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative recovery time	Time from exiting operating room to time ready for hospital discharge	Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Secondary	Preoperative time	Time from patient registration to entering operating room	Time from patient registration to entering operating room, up to 100 hours
Secondary	Intraoperative time	Time from entering to exiting operating room	Time from entering to exiting operating room, up to 100 hours
Secondary	Hospital length of stay	Time from patient registration to ready for hospital discharge	Time from patient registration to ready for hospital discharge, up to 100 hours
Secondary	Postoperative nausea vomiting	Associated symptoms of nausea vomiting, or received non-prophylactic antiemetics	Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Secondary	Severe pain	Any incidence when patient rated pain at least 7 out of 10 numeric rating scale	Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Secondary	Desaturation	Oxygen saturation below 90% with or without oxygen	Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Secondary	Postoperative opioid dose	total postoperative opioid dose in oral morphine equivalents	Time from exiting operating room to time ready for hospital discharge, up to 100 hours