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NCT05193097 Clinical Trial

Vasopressor Preload Modulation During General Anaesthesia

Anesthesia Clinical Trial

Official title:
Vasopressor Preload Modulation During General Anaesthesia

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05193097
Other study ID # H-21032981
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date January 3, 2022
Est. completion date March 31, 2023

Study information
Verified date December 2021
Source Hvidovre University Hospital
Contact Jakob Højlund, MD
Phone 25708807
Email jakob.hoejlund@regionh.dk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Is is debated whether administration of pure vasopressor may augment cardiac output (CO) by means of preload modulation. We wish to test this in 20 patients under general anesthesia, with preload dependency induced by head-up-tilt and preload modulation with infusion of phenylephrine. To document any changes in CO the patients will be monitored by Lithium dilution method. Furthermore we will monitor changes in peripheral perfusion index and test the ability of this non-invasive modality to track changes in CO.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 20
Est. completion date March 31, 2023
Est. primary completion date March 31, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Planned surgery under general anesthesia Exclusion Criteria: - atrial fibrillation - refusal to participate

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Jakob Højlund

Outcome
Type Measure Description Time frame Safety issue
Primary Changes in cardiac output 30 minutes
Primary Changes in peripheral perfusion index 30 minutes
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