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Hypnotic and Anti-nociceptive Components of Magnesium

Anesthesia Clinical Trial

Official title:
Study of the Hypnotic and Anti-nociceptive Components of Magnesium Using Electroencephalogram Spectral Entropy and Pupillometry During Total Intravenous General Anaesthesia

Clinical Trial Summary

The aim of our study is to evaluate the effect of magnesium on the hypnotic effect of propofol.

Clinical Trial Description

The aim of our study is to evaluate the effect of magnesium on the hypnotic effect of propofol. To achieve this, the investigators will analyse the effect of magnesium on the brain concentrations of propofol required to achieve a State Entropy value between 50-60, which corresponds to the recommended depth of anaesthesia. Our study will also evaluate the intraoperative anti- nociceptive effect of magnesium using pupillometry and its two indices, PPI and PRD ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05005494
Study type Interventional
Source University of Liege
Contact Pierre-Yves Hardy, MD
Phone 003242844858
Email pyhardy@chuliege.be
Status Not yet recruiting
Phase Phase 4
Start date September 1, 2021
Completion date December 1, 2021
View Details
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