Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Delta NOL (no unit for the NOL index) |
To compare the variation of NOL (delta NOL) after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Delta Heart Rate (beat per minute) |
To compare the variation of heart rate after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Delta Mean Arterial Blood Pressure (unit: mmHg) |
To compare the variation of mean arterial blood pressure (MABP) after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Delta BIS (no unit for BIS index) |
To compare the variation of bispectral index (BIS) after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Peak value of NOL (no unit) |
To compare the peak value of NOL after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Peak value of Heart Rate (unit: beat per minute) |
To compare the peak value of heart rate after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Peak value of Mean Arterial Blood Pressure (unit: mmHg) |
To compare the peak value of mean arterial blood pressure (MABP) after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Peak value of BIS (no unit) |
To compare the peak value of bispectral index (BIS) after tetanic stimulation under general anesthesia based on propofol versus sevoflurane |
From 1 minute before to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Area Under the Curve for NOL for Propofol Versus Sevoflurane (no unit) |
To compare the area under the curve between propofol and sevoflurane between the beginning of stimulation and 3 minutes after stimulation |
From T0 (start stimulation) to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Area Under the Curve for Heart Rate for Propofol Versus Sevoflurane (no unit) |
To compare the area under the curve between propofol and sevoflurane between the beginning of stimulation and 3 minutes after stimulation |
From T0 (start stimulation) to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Area Under the Curve for Mean Arterial Blood Pressure for Propofol Versus Sevoflurane (no unit) |
To compare the area under the curve between propofol and sevoflurane between the beginning of stimulation and 3 minutes after stimulation |
From T0 (start stimulation) to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Area Under the Curve for BIS for Propofol Versus Sevoflurane (no unit) |
To compare the area under the curve between propofol and sevoflurane between the beginning of stimulation and 3 minutes after stimulation |
From T0 (start stimulation) to 3 minutes after tetanic stimulation for each patient |
|
Secondary |
Total Dose of Remifentanil (unit: mcg) |
Total dose of remifentanil in mcg from induction of anesthesia until tracheal extubation |
Intraoperative |
|
Secondary |
Total Dose of Propofol (unit: mg) |
Total dose of propofol in mg from induction of anesthesia until tracheal extubation in Propofol group |
Intraoperative |
|
Secondary |
Total Dose of Sevoflurane (unit: mL) |
Total dose of sevoflurane in mL from induction of anesthesia until tracheal extubation in Sevoflurane group |
Intraoperative |
|
Secondary |
Total Dose of Hydromorphone in post-anesthesia care unit (PACU) (unit: mg) |
Total dose of hydromorphone in mg in post-anesthesia care unit |
From entrance in post-anesthesia care unit until post-anesthesia care unit discharge, an average of 2 hours |
|
Secondary |
post-anesthesia care unit (PACU) Pain Scores at Rest (scale from 0 to 10) |
Pain scores on a scale from 0 to 10 at rest in post-anesthesia care unit |
From entrance in post-anesthesia care unit until post-anesthesia care unit discharge, an average of 2 hours |
|
Secondary |
post-anesthesia care unit (PACU) Pain Scores during Cough (scale from 0 to 10) |
Pain scores on a scale from 0 to 10 during cough effort in post-anesthesia care unit |
From entrance in post-anesthesia care unit until post-anesthesia care unit discharge, an average of 2 hours |
|