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NCT04510337 Clinical Trial

Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects Depth of Blockade

Anesthesia Clinical Trial

Official title:
Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects the Depth of Blockade in Cancer Patients Undergoing Direct Laryngoscope Surgical Procedures

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04510337
Other study ID # 201617031.2P
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 2, 2018
Est. completion date February 20, 2021

Study information
Verified date March 2021
Source National Cancer Institute, Egypt
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study aim is to compare the effect of magnesium sulphate combined with low dose rocuronium versus standard dose rocuronium

Description:

Comparing the effect of magnesium sulphate combined to low dose rocuronium versus standard dose rocuronium in cancer patients undergoing direct laryngoscopy for laryngeal tumors regarding intubating conditions, intraoperative relaxation, depth of anesthesia and recovery time.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date February 20, 2021
Est. primary completion date February 20, 2021
Accepts healthy volunteers No
Gender All
Age group 30 Years to 70 Years
Eligibility Inclusion Criteria: Patients with Laryngeal tumors ASA I-II Age 30-70 years Exclusion Criteria: Renal and or hepatic insufficiency Neuromuscular disease Large glottic and/or supra-glottic lesions with or without breathing difficulties Known allergy to any of the used drug

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• standard rocuronium dose
0.6 mg/kg rocuronium during induction of anesthesia
• Magnesium sulfate
50 mg/kg magnesium sulphate added to 0.40 mg/kg rocuronium

Locations
Country Name City State
Egypt National Cancer Institute Cairo

Sponsors (1)
Lead Sponsor Collaborator
National Cancer Institute, Egypt

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Onset and duration of muscle relaxant Onset time of muscle relaxant and duration 90 minutes
Secondary Degree of muscle relaxation depth of blockade 90 minutes
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